SCHEMBL8130253

SCHEMBL8130253

CCNC(=O)C(C)=CN1CCOCC1

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HTT P42858 4/20 0.50
ALDH1A1 P00352 3/20 0.38
GAA P10253 3/20 0.38
RECQL P46063 1/20 0.37
SMN1; SMN2 Q16637 3/20 0.36
KMT2A Q03164 1/20 0.36
PIK3CA P42336 1/20 0.35
MTOR P42345 1/20 0.35
PIK3CG P48736 1/20 0.35
TSHR P16473 2/20 0.35
TDP1 Q9NUW8 1/20 0.35
LMNA P02545 1/20 0.34
POLB P06746 1/20 0.34
HPGD P15428 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6450597 0.81 RECQL (0.40) HTTALDH1A1GAARECQLSMN1; SMN2
SCHEMBL4416632 0.74 SMN1; SMN2 (0.43) HTTALDH1A1GAARECQLSMN1; SMN2
SCHEMBL340385 0.74 SMN1; SMN2 (0.43) HTTALDH1A1GAARECQLSMN1; SMN2
SCHEMBL3335814 0.74 RECQL (0.56) HTTALDH1A1GAARECQLSMN1; SMN2
SCHEMBL4744923 0.74 HTT (0.55) HTTALDH1A1GAARECQLSMN1; SMN2
SCHEMBL3129793 0.73 ALDH1A1 (0.57) ALDH1A1GAARECQLKMT2ATSHR
SCHEMBL150342 0.73 SMN1; SMN2 (0.42) HTTALDH1A1GAARECQLSMN1; SMN2
SCHEMBL609261 0.73 SMN1; SMN2 (0.42) HTTALDH1A1GAARECQLSMN1; SMN2
SCHEMBL1062752 0.69 HTT (0.62) HTTALDH1A1RECQLSMN1; SMN2KMT2A
SCHEMBL13368454 0.68 TDP1 (0.69) HTTALDH1A1GAATSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6051361-A PHOTOSENSITIVE MIXTURE COMPRISING A COMPOUND CAPABLE OF GENERATING AN ACID ON EXPOSURE OF ACTINIC LIGHT, A COMPOUND CAN BE CROSSLINKING BY AN ACID, AN INFRARED ABSORBER AND AN ADDITIONAL POLYMER KONICA CORPORATION (JP) 2000-04-18 US disclosed
EP-0903225-A2 Light sensitive composition and image forming material KONICA CORPORATION (JP) 1999-03-24 EP disclosed