SCHEMBL7976882

SCHEMBL7976882

CCNC(=O)[N]N1CCOCC1

nearest known ligand 0.55

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HTT P42858 3/20 0.55
TSHR P16473 3/20 0.42
KMT2A Q03164 2/20 0.39
RECQL P46063 1/20 0.39
POLB P06746 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
ALDH1A1 P00352 4/20 0.37
LMNA P02545 2/20 0.37
MAPT P10636 1/20 0.37
HPGD P15428 1/20 0.37
RAB9A P51151 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7963375 0.86 HTT (0.45) HTTTSHRKMT2ARECQLPOLB
SCHEMBL1455628 0.76 TSHR (0.56) HTTTSHRKMT2ARECQLPOLB
SCHEMBL951889 0.75 TSHR (0.46) HTTTSHRKMT2ARECQLPOLB
SCHEMBL5274851 0.71 SMN1; SMN2 (0.48) HTTTSHRKMT2ARECQLSMN1; SMN2
SCHEMBL968488 0.71 HTT (1.00) HTTTSHRKMT2ARECQLSMN1; SMN2
SCHEMBL8429732 0.68 SMN1; SMN2 (0.72) HTTTSHRKMT2APOLBSMN1; SMN2
SCHEMBL4160204 0.67 KDM4E (0.45) HTTTSHRKMT2ASMN1; SMN2LMNA
SCHEMBL4744923 0.67 HTT (0.55) HTTTSHRKMT2ARECQLSMN1; SMN2
SCHEMBL16385649 0.66 SMN1; SMN2 (0.63) HTTTSHRKMT2ASMN1; SMN2ALDH1A1
SCHEMBL29902875 0.66 HTT (0.53) HTTTSHRKMT2APOLBSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001007409-A1 CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS ASTRAZENECA UK LIMITED (GB) 2001-02-01 WO disclosed
EP-0431568-B1 Method for processing a silver halide photographic material FUJI PHOTO FILM CO LTD (JP) 1996-10-16 EP disclosed
US-5415983-A Method for processing a silver halide photographic material FUJI PHOTO FILM CO., LTD. (JP) 1995-05-16 US disclosed
EP-0283041-B1 DIRECT POSITIVE SILVER HALIDE PHOTOSENSITIVE MATERIAL AND METHOD FOR FORMING DIRECT POSITIVE IMAGE FUJI PHOTO FILM CO., LTD. (JP) 1992-10-07 EP disclosed
EP-0431568-A1 Method for processing a silver halide photographic material FUJI PHOTO FILM CO., LTD. (JP) 1991-06-12 EP disclosed
US-4952483-A NOVEL HYDRAZINE NUCLEATING AGENTS AND ACCELERATORS FUJI PHOTO FILM CO., LTD. (JP) 1990-08-28 US disclosed
US-4871653-A DEVELOPING IN PRESENCE OF MERCAPTO POLYAZAINDENE PROMOTERS AND NUCLEATING QUATERNARY OR HYDRAZIDE-TYPE COMPOUNDS FUJI PHOTO FILM CO., LTD. (JP) 1989-10-03 US disclosed
EP-0283041-A1 Direct positive silver halide photosensitive material and method for forming direct positive image FUJI PHOTO FILM CO., LTD. (JP) 1988-09-21 EP disclosed