Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | MBNL1 | Q9NR56 | 1/20 | 0.45 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | NQO2 | P16083 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31314315 | 1.00 | TDP1 (0.53) | TDP1PDE10AALDH1A1KDM4EGAA | |
| Quinoline SCHEMBL28278392 | 0.89 | ALDH1A1 (0.52) | TDP1PDE10AALDH1A1KDM4EGAA | |
| SCHEMBL18024022 | 0.81 | TDP1 (0.53) | TDP1PDE10AALDH1A1KDM4EGAA | |
| SCHEMBL8026750 | 0.78 | ALDH1A1 (0.65) | TDP1ALDH1A1KDM4EGAAHPGD | |
| SCHEMBL30824519 | 0.77 | ALDH1A1 (0.49) | TDP1ALDH1A1KDM4EGAAHPGD | |
| SCHEMBL3232438 | 0.77 | ALDH1A1 (0.49) | TDP1ALDH1A1KDM4EGAAHPGD | |
| SCHEMBL13405536 | 0.77 | ALDH1A1 (0.49) | TDP1ALDH1A1KDM4EGAAHPGD | |
| SCHEMBL4961476 | 0.77 | ALDH1A1 (0.58) | ALDH1A1KDM4EGAAHPGDGLA | |
| SCHEMBL31105792 | 0.77 | ALDH1A1 (0.49) | TDP1ALDH1A1KDM4EGAAHPGD | |
| SCHEMBL28326811 | 0.77 | ALDH1A1 (0.49) | TDP1ALDH1A1KDM4EGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109473198-A | Preventing fraudulent use of electricity service entrance cable and its preparation process | 江苏亨通电力电缆有限公司 | 2019-03-15 | — | — | CN | disclosed |
| CN-104010504-B | Quinoline carboxamide and quinoline carbonitrile derivatives as mGluR2 negative allosteric modulators, compositions, and uses thereof | MERCK SHARP & DOHME CORP. (US) | 2016-04-06 | — | — | CN | disclosed |
| US-20080293712-A1 | Benzo[C][2,7]Naphtyridine Derivatives, Methods of Making Thereof and Methods of Use Thereof | WYETH (US) | 2008-11-27 | — | — | US | disclosed |
| WO-2008109613-A1 | BENZO[C][2,7]NAPHTHYRIDINE DERIVATIVES, AND THEIR USE AS KINASE INHIBITORS | WYETH (US) | 2008-09-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293712-A1 | Benzo[C][2,7]Naphtyridine Derivatives, Methods of Making Thereof and Methods of Use Thereof | PDPK1, PDK2, PDK3 | TDP1 863/4885PDE10A 464/4885ALDH1A1 2573/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.