Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL428737 | 0.81 | GAA (0.31) | GAA | |
| SCHEMBL1549645 | 0.74 | DGAT1 (0.39) | — | |
| SCHEMBL28577139 | 0.69 | GAA (0.38) | GAA | |
| SCHEMBL16761003 | 0.67 | ALDH1A1 (0.30) | — | |
| SCHEMBL1449319 | 0.67 | — | — | |
| SCHEMBL28731632 | 0.67 | — | — | |
| SCHEMBL5837076 | 0.67 | — | — | |
| SCHEMBL21693751 | 0.66 | NPSR1 (0.35) | — | |
| SCHEMBL331977 | 0.65 | TDP1 (0.31) | — | |
| SCHEMBL10253908 | 0.65 | GAA (0.35) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101563084-B | 4-(1-amino-ethyl)-cyclohexylamine derivatives | ACTELION PHARMACEUTICALS LTD | 2013-02-20 | — | — | CN | disclosed |
| CN-101563084-A | 4-(1-amino-ethyl)-cyclohexylamine derivatives | ACTELION PHARMACEUTICALS LTD (CH) | 2009-10-21 | — | — | CN | disclosed |
| WO-2008109104-A1 | BIVALENT INHIBITORS OF AKT PROTEIN KINASE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-09-12 | — | — | WO | disclosed |