Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 5/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | SHBG | P04278 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 2/20 | 0.31 |
| ▸ | CTSB | P07858 | 2/20 | 0.31 |
| ▸ | CTSH | P09668 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8075546 | 0.97 | SHBG (0.37) | CTSKLTA4HSHBGMEN1KMT2A | |
| SCHEMBL6620420 | 0.95 | CTSK (0.31) | CTSKLTA4H | |
| SCHEMBL12817708 | 0.95 | SHBG (0.39) | CTSKSHBGMEN1KMT2ACYP1A2 | |
| SCHEMBL5479967 | 0.92 | SHBG (0.42) | CTSKSHBGMEN1KMT2ACYP1A2 | |
| SCHEMBL7392023 | 0.92 | SHBG (0.42) | CTSKSHBGMEN1KMT2ACYP1A2 | |
| SCHEMBL24622520 | 0.92 | SHBG (0.42) | CTSKSHBGMEN1KMT2ACYP1A2 | |
| SCHEMBL5460788 | 0.92 | SHBG (0.42) | CTSKSHBGMEN1KMT2ACYP1A2 | |
| SCHEMBL2339293 | 0.92 | SHBG (0.42) | CTSKSHBGMEN1KMT2ACYP1A2 | |
| SCHEMBL2554864 | 0.89 | — | — | |
| SCHEMBL11466074 | 0.80 | CTSK (0.34) | CTSKLTA4HKMT2ACTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008104756-A1 | UREA DERIVATIVES AND THEIR THERAPEUTIC USE | SERENTIS LIMITED (GB) | 2008-09-04 | — | — | WO | disclosed |