Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29230313 | 0.79 | ALDH1A1 (0.33) | ALDH1A1MAPTPTGS1 | |
| SCHEMBL29230314 | 0.79 | ALDH1A1 (0.33) | ALDH1A1MAPTPTGS1 | |
| SCHEMBL3440469 | 0.79 | ALDH1A1 (0.33) | ALDH1A1MAPTPTGS1 | |
| SCHEMBL5444709 | 0.78 | DPP4 (0.31) | DPP4 | |
| Hydrochloric Acid SCHEMBL29230337 | 0.77 | ALDH1A1 (0.32) | ALDH1A1MAPTPTGS1 | |
| Hydrochloric Acid SCHEMBL29230339 | 0.77 | ALDH1A1 (0.32) | ALDH1A1MAPTPTGS1 | |
| SCHEMBL57617 | 0.76 | MMP13 (0.33) | — | |
| SCHEMBL8703006 | 0.73 | TP53 (0.33) | ALDH1A1MAPTPTGS1 | |
| SCHEMBL27465305 | 0.73 | ALDH1A1 (0.37) | ALDH1A1MAPT | |
| SCHEMBL29053822 | 0.72 | ALDH1A1 (0.43) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008104755-A1 | SUCCINATE DERIVATIVES AND THEIR THERAPEUTIC USE | SERENTIS LIMITED (GB) | 2008-09-04 | — | — | WO | disclosed |