Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.52 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.52 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.52 |
| ▸ | IDO1 | P14902 | 2/20 | 0.51 |
| ▸ | TDO2 | P48775 | 2/20 | 0.51 |
| ▸ | IDO2 | Q6ZQW0 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.50 |
| ▸ | RAD52 | P43351 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HTR6 | P50406 | 2/20 | 0.45 |
| ▸ | TOP1 | P11387 | 2/20 | 0.45 |
| ▸ | TOP2A | P11388 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30594984 | 0.84 | ADRB1 (0.53) | KDM4EIDO1TDO2IDO2HTR6 | |
| SCHEMBL29125442 | 0.84 | KMT2A (0.57) | KDM4ESMN1; SMN2NPC1RAB9ATDO2 | |
| SCHEMBL4745451 | 0.83 | KDM4E (0.56) | KDM4ESMN1; SMN2NPC1RAB9AADRA2A | |
| SCHEMBL27909494 | 0.81 | KDM4E (0.48) | KDM4ESMN1; SMN2NPC1RAB9AIDO1 | |
| SCHEMBL29125356 | 0.78 | MAPT (0.49) | SMN1; SMN2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL30594931 | 0.78 | MAPT (0.49) | SMN1; SMN2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL13312472 | 0.76 | AURKA (0.53) | KDM4ESMN1; SMN2NPC1RAB9AIDO1 | |
| SCHEMBL25746316 | 0.74 | KDM4E (0.56) | KDM4ESMN1; SMN2NPC1RAB9AADRA2A | |
| SCHEMBL27170983 | 0.74 | KDM4E (0.56) | KDM4ESMN1; SMN2NPC1RAB9AADRA2A | |
| SCHEMBL11762820 | 0.74 | KDM4E (0.45) | KDM4ESMN1; SMN2NPC1RAB9AIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117079-A1 | ANTIMICROBIAL COMPOUNDS BASED UPON 4-AMINOQUINOLINE | HELPERBY THERAPEUTICS LIMITED (GB) | 2008-10-02 | — | — | WO | disclosed |