Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.52 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.52 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.52 |
| ▸ | HTR6 | P50406 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.50 |
| ▸ | RAD52 | P43351 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 2/20 | 0.48 |
| ▸ | TDO2 | P48775 | 2/20 | 0.48 |
| ▸ | IDO2 | Q6ZQW0 | 2/20 | 0.48 |
| ▸ | HTR3A | P46098 | 2/20 | 0.46 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23999557 | 0.84 | KMT2A (0.54) | KDM4ENPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL4745320 | 0.83 | KDM4E (0.56) | KDM4ENPC1RAB9ASMN1; SMN2ADRA2A | |
| SCHEMBL27170983 | 0.80 | KDM4E (0.56) | KDM4ENPC1RAB9ASMN1; SMN2ADRA2A | |
| SCHEMBL23999932 | 0.77 | NPSR1 (0.53) | KDM4ERAB9ALMNAMEN1GAA | |
| SCHEMBL23999899 | 0.76 | LMNA (0.46) | KDM4ENPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL25826546 | 0.76 | LMNA (0.46) | KDM4ENPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL4808109 | 0.75 | KDM4E (0.66) | KDM4ENPC1RAB9ASMN1; SMN2HTR6 | |
| SCHEMBL25746316 | 0.74 | KDM4E (0.56) | KDM4ENPC1RAB9ASMN1; SMN2ADRA2A | |
| SCHEMBL6890186 | 0.73 | IDO1 (0.59) | KDM4ENPC1RAB9ASMN1; SMN2HTR6 | |
| SCHEMBL3642734 | 0.73 | LMNA (0.49) | KDM4ENPC1RAB9ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117079-A1 | ANTIMICROBIAL COMPOUNDS BASED UPON 4-AMINOQUINOLINE | HELPERBY THERAPEUTICS LIMITED (GB) | 2008-10-02 | — | — | WO | disclosed |