Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | EGFR | P00533 | 4/20 | 0.53 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.53 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.53 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.53 |
| ▸ | ABL1 | P00519 | 1/20 | 0.53 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.53 |
| ▸ | PIM1 | P11309 | 1/20 | 0.53 |
| ▸ | PRKACA | P17612 | 1/20 | 0.53 |
| ▸ | LTK | P29376 | 1/20 | 0.53 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.53 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.53 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.53 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.53 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.53 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.53 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.53 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31004010 | 1.00 | ADORA3 (0.65) | ADORA3LMNAALDH1A1EGFRABCG2 | |
| SCHEMBL4751092 | 0.83 | ADORA3 (0.56) | ADORA3LMNAALDH1A1EGFRABCG2 | |
| SCHEMBL28645156 | 0.83 | ADORA3 (0.65) | ADORA3LMNAALDH1A1EGFRABCG2 | |
| SCHEMBL4424939 | 0.83 | ADORA3 (0.56) | ADORA3LMNAALDH1A1EGFRABCG2 | |
| SCHEMBL31060719 | 0.79 | ADORA3 (1.00) | ADORA3LMNAEGFRABCG2DAPK3 | |
| SCHEMBL4689838 | 0.79 | ADORA3 (1.00) | ADORA3LMNAEGFRABCG2DAPK3 | |
| SCHEMBL18552030 | 0.76 | EGFR (0.61) | ADORA3LMNAALDH1A1EGFRABCG2 | |
| SCHEMBL30317647 | 0.76 | EGFR (0.61) | ADORA3LMNAEGFRABCG2DAPK3 | |
| SCHEMBL3874722 | 0.76 | EGFR (0.61) | ADORA3LMNAEGFRABCG2DAPK3 | |
| SCHEMBL21879270 | 0.75 | ALDH1A1 (0.57) | ADORA3LMNAALDH1A1EGFRABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1296973-B1 | GUANIDINE DERIVATIVES OF QUINAZOLINE FOR USE IN THE TREATMENT OF AUTOIMMUNE DISEASES | ASTRAZENECA AB (SE) | 2008-11-05 | — | — | EP | disclosed |