Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2620631 | 0.78 | — | — | |
| Water SCHEMBL25401298 | 0.74 | — | — | |
| SCHEMBL1809810 | 0.74 | L3MBTL1 (0.32) | POLB | |
| SCHEMBL2236435 | 0.74 | — | — | |
| SCHEMBL12346153 | 0.73 | KDM4E (0.31) | — | |
| SCHEMBL19066501 | 0.72 | KMT2A (0.33) | — | |
| SCHEMBL1564365 | 0.70 | — | — | |
| SCHEMBL6135374 | 0.70 | — | — | |
| SCHEMBL1701639 | 0.70 | — | — | |
| SCHEMBL21257861 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250114374-A1 | BCL-2 INHIBITORS | NEWAVE PHARMACEUTICAL INC. | 2025-04-10 | — | — | US | disclosed |
| US-20240166646-A1 | 1H-PYRROLO[2,3-B]PYRIDINE DERIVATIVES AS BCL-2 INHIBITORS FOR THE TREATMENT OF NEOPLASTIC AND AUTOIMMUNE DISEASES | NEWAVE PHARMACEUTICAL INC. | 2024-05-23 | — | — | US | disclosed |
| US-20240083917-A1 | Polycyclic Kinase Inhibitor | Xuanzhu Biopharmaceutical Co., Ltd. (CN) | 2024-03-14 | — | — | US | disclosed |
| EP-4289853-A1 | POLYCYCLIC KINASE INHIBITOR | Shandong Xuanzhu Pharma Co., Ltd. (CN) | 2023-12-13 | — | — | EP | disclosed |
| EP-4289853-A1 | POLYCYCLIC KINASE INHIBITOR | Shandong Xuanzhu Pharma Co., Ltd. (CN) | 2023-12-13 | — | — | EP | disclosed |
| CN-116669741-A | Polycyclic kinase inhibitors | 山东轩竹医药科技有限公司 | 2023-08-29 | — | — | CN | disclosed |
| WO-2023122000-A1 | BCL-2 INHIBITORS | NEWAVE PHARMACEUTICAL INC. (US) | 2023-06-29 | — | — | WO | disclosed |
| WO-2022148354-A1 | POLYCYCLIC KINASE INHIBITOR | 山东轩竹医药科技有限公司 | 2022-07-14 | — | — | WO | disclosed |
| WO-2022148354-A1 | POLYCYCLIC KINASE INHIBITOR | 山东轩竹医药科技有限公司 | 2022-07-14 | — | — | WO | disclosed |
| WO-2022140224-A1 | 1H-PYRROLO[2,3-B]PYRIDINE DERIVATIVES AS BCL-2 INHIBITORS FOR THE TREATMENT OF NEOPLASTIC AND AUTOIMMUNE DISEASES | NEWAVE PHARMACEUTICAL INC. (US) | 2022-06-30 | — | — | WO | disclosed |
| EP-2373619-B1 | GEMINAL ALKOXY/ALKYLSPIROCYCLIC SUBSTITUTED TETRAMIC ACID DERIVATES | BAYER CROPSCIENCE AG (DE) | 2014-09-10 | — | — | EP | disclosed |
| US-20140213795-A1 | GERMINAL ALKOXY/ALKYLSPIROCYCLIC SUBSTITUTED TETRAMATE DERIVATIVES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-07-31 | — | — | US | disclosed |
| US-20140213795-A1 | GERMINAL ALKOXY/ALKYLSPIROCYCLIC SUBSTITUTED TETRAMATE DERIVATIVES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-07-31 | — | — | US | disclosed |
| WO-2014053666-A1 | INHIBITORS OF VIRAL REPLICATION, THEIR PROCESS OF PREPARATION AND THEIR THERAPEUTICAL USES | LABORATOIRE BIODIM (FR) | 2014-04-10 | — | — | WO | disclosed |
| US-8389443-B2 | Geminal alkoxy/alkylspirocyclic substituted tetramate derivatives | BAYER CROPSCIENCE AG (DE) | 2013-03-05 | — | — | US | disclosed |
| US-8389443-B2 | Geminal alkoxy/alkylspirocyclic substituted tetramate derivatives | BAYER CROPSCIENCE AG (DE) | 2013-03-05 | — | — | US | disclosed |
| US-20100261608-A1 | Geminal alkoxy/alkylspirocyclic substituted tetramate derivatives | BAYER CROPSCIENCE AG (DE) | 2010-10-14 | — | — | US | disclosed |
| US-20100261608-A1 | Geminal alkoxy/alkylspirocyclic substituted tetramate derivatives | BAYER CROPSCIENCE AG (DE) | 2010-10-14 | — | — | US | disclosed |
| WO-2008119716-A1 | 1- (1-CYCLOHEXYL-4-PIPERIDINYL) -1, 3-DIHYDRO-2H-BENZIMIDAZOL-2-ONE DERIVATIVES WHICH HAVE ACTIVITY ON THE M1 RECEPTOR AND THEIR USE IN MEDICINE | GLAXO GROUP LIMITED (GB) | 2008-10-09 | — | — | WO | disclosed |
| WO-2008119716-A1 | 1- (1-CYCLOHEXYL-4-PIPERIDINYL) -1, 3-DIHYDRO-2H-BENZIMIDAZOL-2-ONE DERIVATIVES WHICH HAVE ACTIVITY ON THE M1 RECEPTOR AND THEIR USE IN MEDICINE | GLAXO GROUP LIMITED (GB) | 2008-10-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240166646-A1 | 1H-PYRROLO[2,3-B]PYRIDINE DERIVATIVES AS BCL-2 INHIBITORS FOR THE TREATMENT OF NEOPLASTIC AND AUTOIMMUNE DISEASES | BCL2, BCL3, BCL2L1 | POLB 740/4885AVPR1A 4557/4885 |
| US-20250114374-A1 | BCL-2 INHIBITORS | BCL2, BCL2L1, BCL2L10 | POLB 2556/4885AVPR1A 4815/4885 |
| US-20140213795-A1 | GERMINAL ALKOXY/ALKYLSPIROCYCLIC SUBSTITUTED TETRAMATE DERIVATIVES | AGXT, GMNN, GLRX3 | POLB 1374/4885AVPR1A 3624/4885 |
| US-20240083917-A1 | Polycyclic Kinase Inhibitor | PRKDC, DCK, DMPK | POLB 286/4885AVPR1A 2930/4885 |
| US-20100261608-A1 | Geminal alkoxy/alkylspirocyclic substituted tetramate derivatives | GMNN, AGXT, GEMIN5 | POLB 1229/4885AVPR1A 4169/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.