Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC11A2 | P49281 | 3/20 | 0.54 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.44 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.41 |
| ▸ | OXTR | P30559 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.41 |
| ▸ | CDK2 | P24941 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3690425 | 0.87 | SLC11A2 (0.55) | SLC11A2PDCD1CD274MAPTALDH1A1 | |
| SCHEMBL3682387 | 0.86 | SLC11A2 (0.51) | SLC11A2MAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL4746341 | 0.85 | ALDH1A1 (0.48) | SLC11A2MAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL3692788 | 0.83 | MAPT (0.48) | SLC11A2MAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL3689323 | 0.81 | FFAR4 (0.45) | MAPTALDH1A1HPGDHSD17B10ALOX15 | |
| SCHEMBL3683176 | 0.81 | SLC11A2 (0.53) | SLC11A2PDCD1CD274MAPTALDH1A1 | |
| SCHEMBL3683062 | 0.80 | MAPT (0.52) | SLC11A2MAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL3681849 | 0.80 | SLC11A2 (0.54) | SLC11A2MAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL3683412 | 0.79 | MAPT (0.45) | SLC11A2MAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL3693842 | 0.78 | MEN1 (0.42) | MAPTALDH1A1HPGDHSD17B10ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008121861-A2 | PYRAZOLE AND PYRROLE COMPOUNDS USEFUL IN TREATING IRON DISORDERS | XENON PHARMACEUTICALS INC. (CA) | 2008-10-09 | — | — | WO | claimed |
| WO-2008121861-A2 | PYRAZOLE AND PYRROLE COMPOUNDS USEFUL IN TREATING IRON DISORDERS | XENON PHARMACEUTICALS INC. (CA) | 2008-10-09 | — | — | WO | disclosed |
| WO-2008121861-A2 | PYRAZOLE AND PYRROLE COMPOUNDS USEFUL IN TREATING IRON DISORDERS | XENON PHARMACEUTICALS INC. (CA) | 2008-10-09 | — | — | WO | disclosed |