Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | SLC11A2 | P49281 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | CCNA2 | P20248 | 8/20 | 0.44 |
| ▸ | CDK2 | P24941 | 8/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CCNO | P22674 | 1/20 | 0.43 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.43 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3682387 | 0.89 | SLC11A2 (0.51) | ALDH1A1HPGDHSD17B10ALOX15MAPT | |
| SCHEMBL3692788 | 0.89 | MAPT (0.48) | ALDH1A1HPGDHSD17B10ALOX15MAPT | |
| SCHEMBL3683062 | 0.88 | MAPT (0.52) | ALDH1A1HPGDHSD17B10ALOX15MAPT | |
| SCHEMBL3683176 | 0.86 | SLC11A2 (0.53) | ALDH1A1HPGDHSD17B10ALOX15MAPT | |
| SCHEMBL3689323 | 0.86 | FFAR4 (0.45) | ALDH1A1HPGDHSD17B10ALOX15MAPT | |
| SCHEMBL4745571 | 0.85 | SLC11A2 (0.54) | ALDH1A1HPGDHSD17B10ALOX15MAPT | |
| SCHEMBL3681849 | 0.85 | SLC11A2 (0.54) | ALDH1A1HPGDHSD17B10ALOX15MAPT | |
| SCHEMBL3693578 | 0.84 | NPC1 (0.47) | ALDH1A1HPGDMAPTSMN1; SMN2TDP1 | |
| SCHEMBL3683672 | 0.84 | ALDH1A1 (0.50) | ALDH1A1HPGDHSD17B10ALOX15MAPT | |
| SCHEMBL3683412 | 0.84 | MAPT (0.45) | ALDH1A1HPGDHSD17B10ALOX15MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008121861-A2 | PYRAZOLE AND PYRROLE COMPOUNDS USEFUL IN TREATING IRON DISORDERS | XENON PHARMACEUTICALS INC. (CA) | 2008-10-09 | — | — | WO | disclosed |