Prochloraz

Prochloraz

SCHEMBL4745585

CCCN(CCOc1c(Cl)cc(Cl)cc1Cl)C(=O)n1ccnc1.Oc1ccccc1

nearest known ligand 0.85

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 1/20 0.85
ADRB2 P07550 3/20 0.37
ADRB1 P08588 3/20 0.37
ADRB3 P13945 3/20 0.37
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
KDM4E B2RXH2 3/20 0.34
NR1I2 O75469 1/20 0.34
NR3C1 P04150 1/20 0.34
HTR1A P08908 1/20 0.34
ADORA3 P0DMS8 1/20 0.34
CNR1 P21554 1/20 0.34
TBXA2R P21731 1/20 0.34
SLC6A2 P23975 1/20 0.34
HTR2A P28223 1/20 0.34
HTR2C P28335 1/20 0.34
SLC6A4 P31645 1/20 0.34
ADRA1A P35348 1/20 0.34
OPRK1 P41145 1/20 0.34
HTR2B P41595 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Prochloraz SCHEMBL8180955 0.95 AHR (0.90) AHRADRB2ADRB1ADRB3MEN1
Prochloraz SCHEMBL9316172 0.95 AHR (0.76) AHRADRB2ADRB1ADRB3MEN1
Prochloraz SCHEMBL29353284 0.93 AHR (0.86) AHRADRB2ADRB1ADRB3MEN1
Prochloraz SCHEMBL29551185 0.93 AHR (0.86) AHRADRB2ADRB1ADRB3MEN1
Prochloraz SCHEMBL2128014 0.93 AHR (0.74) AHRADRB2ADRB1ADRB3MEN1
Prochloraz SCHEMBL1263186 0.93 AHR (0.73) AHRADRB2ADRB1ADRB3MEN1
Prochloraz SCHEMBL7381517 0.93 AHR (0.85) AHRADRB2ADRB1ADRB3MEN1
Prochloraz SCHEMBL9291992 0.92 AHR (0.88) AHRADRB2ADRB1ADRB3MEN1
Prochloraz SCHEMBL34675 0.92 AHR (1.00) AHRADRB2ADRB1ADRB3MEN1
Prochloraz SCHEMBL22242 0.92 AHR (1.00) AHRADRB2ADRB1ADRB3MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008117019-A1 TLR4 LIGAND ISOLATED FROM HONEY UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) 2008-10-02 WO disclosed