Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Prochloraz. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.76 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ADH5 | P11766 | 1/20 | 0.33 |
| ▸ | WEE1 | P30291 | 1/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Prochloraz SCHEMBL4745585 | 0.95 | AHR (0.85) | AHRADRB2ADRB1ADRB3MEN1 | |
| Prochloraz SCHEMBL8536273 | 0.92 | AHR (0.80) | AHRTBXAS1MRGPRX4ADRB2ADRB1 | |
| Prochloraz SCHEMBL8180955 | 0.92 | AHR (0.90) | AHRADRB2ADRB1ADRB3MEN1 | |
| Prochloraz SCHEMBL9320347 | 0.89 | AHR (0.78) | AHRADRB2ADRB1ADRB3LMNA | |
| Prochloraz SCHEMBL11404537 | 0.89 | AHR (0.83) | AHRADRB2ADRB1ADRB3MEN1 | |
| Prochloraz SCHEMBL29353284 | 0.89 | AHR (0.86) | AHRADRB2ADRB1ADRB3MEN1 | |
| Prochloraz SCHEMBL29551185 | 0.89 | AHR (0.86) | AHRADRB2ADRB1ADRB3MEN1 | |
| Prochloraz SCHEMBL5493293 | 0.88 | AHR (0.74) | AHRADRB2ADRB1ADRB3MEN1 | |
| Prochloraz SCHEMBL2128014 | 0.88 | AHR (0.74) | AHRADRB2ADRB1ADRB3MEN1 | |
| Prochloraz SCHEMBL1263186 | 0.88 | AHR (0.73) | AHRADRB2ADRB1ADRB3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5298591-A | Clarity, heat resistance, terephthalic acid, bisphenol A p-hydroxybenzoic acid | HOECHST CELANESE CORP. (US) | 1994-03-29 | — | — | US | disclosed |