Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.52 |
| ▸ | STAT1 | P42224 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | TERT | O14746 | 3/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | IGF1R | P08069 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.32 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.32 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.32 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.32 |
| ▸ | BRSK1 | Q8TDC3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6711729 | 0.91 | STAT3 (0.49) | STAT3STAT1TERTMAOADYRK1A | |
| SCHEMBL1854874 | 0.84 | STAT3 (0.55) | STAT3STAT1HDAC6TERTCHEK2 | |
| SCHEMBL585272 | 0.84 | STAT3 (0.55) | STAT3STAT1HDAC6MAOACHEK2 | |
| SCHEMBL1861760 | 0.84 | STAT3 (0.52) | STAT3STAT1MAOACHEK2DYRK3 | |
| SCHEMBL584793 | 0.84 | STAT3 (0.52) | STAT3STAT1HDAC6TERTCHEK2 | |
| SCHEMBL585528 | 0.84 | STAT3 (0.62) | STAT3STAT1DYRK1AAURKACLK4 | |
| SCHEMBL31055740 | 0.84 | STAT3 (0.62) | STAT3STAT1DYRK1AAURKACLK4 | |
| Hydrochloric Acid SCHEMBL29883333 | 0.83 | STAT3 (0.51) | STAT3STAT1HDAC6TERTCHEK2 | |
| Hydrochloric Acid SCHEMBL584374 | 0.83 | STAT3 (0.51) | STAT3STAT1HDAC6TERTCHEK2 | |
| SCHEMBL1856477 | 0.82 | STAT3 (0.50) | STAT3STAT1HDAC6CHEK2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008119950-A1 | PORPHYRIN COMPOUNDS | ISIS INNOVATION LIMITED (GB) | 2008-10-09 | — | — | WO | disclosed |