Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.35 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.34 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | IGF1R | P08069 | 1/20 | 0.31 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethylamine SCHEMBL1861764 | 0.84 | KDM4E (0.38) | ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL585273 | 0.84 | MAOA (0.34) | CYP1A2CYP2C19 | |
| SCHEMBL1854878 | 0.84 | PDE2A (0.37) | ALDH1A1CYP1A2CYP2C19PIM1 | |
| SCHEMBL2325507 | 0.83 | CYP1A2 (0.32) | CYP1A2CYP2C19 | |
| SCHEMBL585529 | 0.83 | CLK4 (0.39) | ALDH1A1USP2CYP1A2CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL584375 | 0.82 | CHRNB2 (0.33) | CYP1A2CYP2C19 | |
| SCHEMBL1856480 | 0.82 | FFAR1 (0.35) | CYP1A2CYP2C19 | |
| SCHEMBL2202844 | 0.79 | TSHR (0.37) | CYP1A2CYP2C19TSHR | |
| Dimethylamine SCHEMBL1859717 | 0.76 | DHODH (0.33) | DHODH | |
| SCHEMBL2360345 | 0.74 | CYP1A2 (0.32) | CYP1A2CYP2C19TSHRHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008119950-A1 | PORPHYRIN COMPOUNDS | ISIS INNOVATION LIMITED (GB) | 2008-10-09 | — | — | WO | disclosed |