Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 2/20 | 0.36 |
| ▸ | LYN | P07948 | 2/20 | 0.36 |
| ▸ | SRC | P12931 | 2/20 | 0.36 |
| ▸ | CSK | P41240 | 2/20 | 0.36 |
| ▸ | BTK | Q06187 | 2/20 | 0.36 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.36 |
| ▸ | MEN1 | O00255 | 9/20 | 0.36 |
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.36 |
| ▸ | NPC1 | O15118 | 5/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | POLB | P06746 | 6/20 | 0.35 |
| ▸ | HTT | P42858 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4745921 | 1.00 | LCK (0.36) | LCKLYNSRCCSKBTK | |
| SCHEMBL4367136 | 0.88 | PTGS2 (0.49) | LCKLYNSRCCSKBTK | |
| SCHEMBL4367131 | 0.88 | PTGS2 (0.49) | LCKLYNSRCCSKBTK | |
| SCHEMBL4363237 | 0.87 | KMT2A (0.46) | LCKLYNSRCCSKBTK | |
| SCHEMBL4363239 | 0.87 | KMT2A (0.46) | LCKLYNSRCCSKBTK | |
| SCHEMBL4747996 | 0.84 | MAPT (0.37) | KMT2AMEN1MAPTL3MBTL1NPC1 | |
| SCHEMBL4365890 | 0.82 | KDM1A (0.47) | LCKLYNSRCCSKBTK | |
| SCHEMBL4365886 | 0.82 | KDM1A (0.47) | LCKLYNSRCCSKBTK | |
| SCHEMBL4374636 | 0.81 | LCK (0.57) | LCKLYNSRCCSKBTK | |
| SCHEMBL4374638 | 0.81 | LCK (0.57) | LCKLYNSRCCSKBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008113161-A1 | PHOSPHATE PRODRUGS OF QUINAZOLINYL NITROFURANS, METHODS OF OBTAINING, AND USE OF SAME | ULYSSES PHARMACEUTICAL PRODUCTS INC. (CA) | 2008-09-25 | — | — | WO | disclosed |