Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | MITF | O75030 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4362862 | 0.90 | MAPT (0.46) | MAPTALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL4362857 | 0.90 | MAPT (0.46) | MAPTALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL4361527 | 0.89 | ALDH1A1 (0.44) | MAPTALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL4361528 | 0.89 | ALDH1A1 (0.44) | MAPTALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL4369446 | 0.86 | MAPT (0.40) | MAPTALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL4369449 | 0.86 | MAPT (0.40) | MAPTALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL4375416 | 0.86 | ALDH1A1 (0.44) | MAPTALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL4375422 | 0.86 | ALDH1A1 (0.44) | MAPTALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL4745918 | 0.84 | LCK (0.36) | MAPTALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL4745921 | 0.84 | LCK (0.36) | MAPTALDH1A1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008113161-A1 | PHOSPHATE PRODRUGS OF QUINAZOLINYL NITROFURANS, METHODS OF OBTAINING, AND USE OF SAME | ULYSSES PHARMACEUTICAL PRODUCTS INC. (CA) | 2008-09-25 | — | — | WO | disclosed |