Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.44 |
| ▸ | EBP | Q15125 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4000984 | 1.00 | SIGMAR1 (0.44) | SIGMAR1EBPSMN1; SMN2PDK1KDM4E | |
| SCHEMBL2560730 | 0.78 | SIGMAR1 (0.50) | SIGMAR1EBPPDK1KDM4EHTT | |
| SCHEMBL22772885 | 0.78 | — | — | |
| SCHEMBL16764751 | 0.77 | SIGMAR1 (0.44) | SIGMAR1EBPSMN1; SMN2PDK1KDM4E | |
| SCHEMBL10815846 | 0.77 | SIGMAR1 (0.44) | SIGMAR1EBPSMN1; SMN2PDK1KDM4E | |
| SCHEMBL1072148 | 0.77 | SIGMAR1 (0.44) | SIGMAR1EBPSMN1; SMN2PDK1KDM4E | |
| SCHEMBL29946367 | 0.75 | PDK1 (0.41) | PDK1 | |
| SCHEMBL28976304 | 0.75 | PDK1 (0.41) | PDK1 | |
| SCHEMBL4317035 | 0.74 | MAPK8 (0.39) | SIGMAR1EBPSMN1; SMN2PDK1KDM4E | |
| SCHEMBL14038431 | 0.73 | SIGMAR1 (0.34) | SIGMAR1KDM4EHTTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008112674-A1 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2008-09-18 | — | — | WO | claimed |