SCHEMBL4745935

SCHEMBL4745935

CCOC(CC)C[N+](C)(C)C

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.36
LMNA P02545 3/20 0.35
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
CYP2C19 P33261 1/20 0.34
RECQL P46063 1/20 0.34
PRKD3 O94806 2/20 0.33
PRKCG P05129 2/20 0.33
PRKCB P05771 2/20 0.33
PRKCA P17252 2/20 0.33
PRKCH P24723 2/20 0.33
PRKCI P41743 2/20 0.33
PRKCE Q02156 2/20 0.33
PRKCQ Q04759 2/20 0.33
PRKCZ Q05513 2/20 0.33
PRKCD Q05655 2/20 0.33
PRKD1 Q15139 2/20 0.33
CYP1A2 P05177 4/20 0.32
HRH1 P35367 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluoromethane SCHEMBL27919564 0.95 THRB (0.33) THRBLMNAMEN1KMT2ACYP2C19
SCHEMBL873957 0.80 THRB (0.33) THRBLMNAMEN1KMT2ACYP2C19
SCHEMBL15761656 0.77 PRKD3 (0.41) MEN1KMT2ACYP2C19RECQLPRKD3
SCHEMBL127172 0.76
SCHEMBL14378533 0.76 PRKD3 (0.47) LMNAMEN1KMT2ACYP2C19RECQL
SCHEMBL15761657 0.75 PRKD3 (0.40) MEN1KMT2ACYP2C19RECQLPRKD3
SCHEMBL15761658 0.75 PRKD3 (0.40) MEN1KMT2ACYP2C19RECQLPRKD3
SCHEMBL15761659 0.75 PRKD3 (0.40) MEN1KMT2ACYP2C19RECQLPRKD3
SCHEMBL19522832 0.75 PRKD3 (0.40) MEN1KMT2ACYP2C19RECQLPRKD3
SCHEMBL4558918 0.74 MEN1 (0.38) LMNAMEN1KMT2ACYP2C19RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230101362-A1 RNA STABILIZATION TEAM MEDICAL LLC 2023-03-30 US disclosed
WO-2023044455-A2 RNA STABILIZATION TEAM MEDICAL LLC (US) 2023-03-23 WO disclosed
CN-104510731-A Method for improving autoimmune disease SHANGHAI MANYI TECHNOLOGY CO LTD 2015-04-15 CN disclosed
EP-1893577-A1 BIPHENYL COMPOUNDS USEFUL AS MUSCARINIC RECEPTOR ANTAGONISTS Theravance, Inc. (US) 2008-03-05 EP disclosed
WO-2006138218-A1 BIPHENYL COMPOUNDS USEFUL AS MUSCARINIC RECEPTOR ANTAGONISTS THERAVANCE, INC. (US) 2006-12-28 WO disclosed
US-6395782-B1 Method of increasing longevity and preventing body weight wasting in autoimmune disease by using conjugated linoleic acid WISCONSIN ALUMNI RESEARCH FOUNDATION 2002-05-28 US disclosed