Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.32 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.32 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4745991 | 1.00 | DPP4 (0.33) | DPP4GNAI3GNAO1GNAI1NPC1 | |
| SCHEMBL4745992 | 1.00 | DPP4 (0.33) | DPP4GNAI3GNAO1GNAI1NPC1 | |
| SCHEMBL24834975 | 0.87 | NPC1 (0.34) | NPC1TAAR1 | |
| SCHEMBL602982 | 0.81 | GNAI3 (0.35) | DPP4GNAI3GNAO1GNAI1NPC1 | |
| SCHEMBL602981 | 0.81 | GNAI3 (0.35) | DPP4GNAI3GNAO1GNAI1NPC1 | |
| Hydrochloric Acid SCHEMBL601271 | 0.80 | GNAI3 (0.38) | DPP4GNAI3GNAO1GNAI1NPC1 | |
| Hydrochloric Acid SCHEMBL601270 | 0.80 | GNAI3 (0.38) | DPP4GNAI3GNAO1GNAI1NPC1 | |
| SCHEMBL4745773 | 0.79 | TAAR1 (0.34) | TAAR1 | |
| SCHEMBL4745776 | 0.79 | TAAR1 (0.34) | TAAR1 | |
| SCHEMBL4745772 | 0.79 | TAAR1 (0.34) | TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008119715-A1 | 1- (1-CYCLOHEXYL-4-PIPERIDINYL) -1, 3-DIHYDRO-2H-BENZIMIDAZOL-2-ONE DERIVATIVES WHICH HAVE ACTIVITY ON THE M1 RECEPTOR AND THEIR USE IN MEDICINE | GLAXO GROUP LIMITED (GB) | 2008-10-09 | — | — | WO | disclosed |