Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.65 |
| ▸ | PPARG | P37231 | 13/20 | 0.53 |
| ▸ | PPARA | Q07869 | 12/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4748206 | 0.93 | KDM4E (0.54) | ALDH1A1KDM4EPPARGPPARAPPARD | |
| SCHEMBL4748204 | 0.93 | KDM4E (0.54) | ALDH1A1KDM4EPPARGPPARAPPARD | |
| SCHEMBL4744029 | 0.92 | PPARG (0.55) | ALDH1A1KDM4EPPARGPPARA | |
| SCHEMBL4744592 | 0.92 | PPARG (0.55) | ALDH1A1KDM4EPPARGPPARA | |
| SCHEMBL4747026 | 0.91 | PPARG (0.53) | ALDH1A1KDM4EPPARGPPARASMN1; SMN2 | |
| SCHEMBL4747028 | 0.91 | PPARG (0.53) | ALDH1A1KDM4EPPARGPPARASMN1; SMN2 | |
| SCHEMBL4788193 | 0.91 | PPARG (0.52) | ALDH1A1KDM4EPPARGPPARAPPARD | |
| SCHEMBL4788199 | 0.91 | PPARG (0.52) | ALDH1A1KDM4EPPARGPPARAPPARD | |
| SCHEMBL4744028 | 0.89 | PPARG (0.56) | PPARGPPARAPPARD | |
| SCHEMBL4748056 | 0.89 | PPARG (0.56) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117982-A1 | HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR INHIBITING LIPID ACCUMULATION CONTAINING SAME | CRYSTAL GENOMICS, INC. (KR) | 2008-10-02 | — | — | WO | disclosed |