Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 17/20 | 0.56 |
| ▸ | PPARA | Q07869 | 15/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | PPARD | Q03181 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4748056 | 1.00 | PPARG (0.56) | PPARGPPARACYP2C9CYP2C19CYP3A4 | |
| SCHEMBL4744029 | 0.98 | PPARG (0.55) | PPARGPPARACYP2C9CYP2C19CYP3A4 | |
| SCHEMBL4744592 | 0.98 | PPARG (0.55) | PPARGPPARACYP2C9CYP2C19CYP3A4 | |
| SCHEMBL4747359 | 0.95 | PPARG (0.57) | PPARGPPARACYP2C9CYP2C19CYP3A4 | |
| SCHEMBL4744011 | 0.95 | PPARG (0.57) | PPARGPPARACYP2C9CYP2C19CYP3A4 | |
| SCHEMBL4746574 | 0.93 | ALDH1A1 (0.49) | PPARGPPARACYP2C9KCNH2PPARD | |
| SCHEMBL4748235 | 0.93 | ALDH1A1 (0.49) | PPARGPPARACYP2C9KCNH2PPARD | |
| SCHEMBL4748026 | 0.93 | ALDH1A1 (0.49) | PPARGPPARACYP2C9KCNH2PPARD | |
| SCHEMBL4788199 | 0.92 | PPARG (0.52) | PPARGPPARAPPARD | |
| SCHEMBL4788193 | 0.92 | PPARG (0.52) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117982-A1 | HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR INHIBITING LIPID ACCUMULATION CONTAINING SAME | CRYSTAL GENOMICS, INC. (KR) | 2008-10-02 | — | — | WO | claimed |
| WO-2008117982-A1 | HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR INHIBITING LIPID ACCUMULATION CONTAINING SAME | CRYSTAL GENOMICS, INC. (KR) | 2008-10-02 | — | — | WO | disclosed |