Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.56 |
| ▸ | PPARG | P37231 | 13/20 | 0.47 |
| ▸ | PPARA | Q07869 | 11/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | DRD4 | P21917 | 2/20 | 0.46 |
| ▸ | DRD3 | P35462 | 2/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 3/20 | 0.40 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.39 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4787746 | 0.88 | NPC1 (0.43) | FFAR1PPARGPPARAHRH3 | |
| SCHEMBL7159209 | 0.87 | FFAR1 (0.56) | FFAR1PPARGPPARADRD2DRD4 | |
| SCHEMBL4748088 | 0.87 | FFAR1 (0.59) | FFAR1PPARGPPARADRD2DRD4 | |
| SCHEMBL4744857 | 0.87 | FFAR1 (0.68) | FFAR1PPARGPPARADRD2DRD4 | |
| SCHEMBL5099205 | 0.86 | FFAR1 (0.60) | FFAR1PPARGPPARADRD2DRD4 | |
| SCHEMBL4748030 | 0.84 | PPARG (0.57) | FFAR1PPARGPPARAHRH3PPARD | |
| SCHEMBL7210573 | 0.84 | FFAR1 (0.52) | FFAR1PPARGPPARADRD2DRD4 | |
| SCHEMBL5111304 | 0.84 | FFAR1 (0.58) | FFAR1PPARGPPARADRD2DRD4 | |
| SCHEMBL8839945 | 0.84 | FFAR1 (0.53) | FFAR1PPARGPPARADRD2DRD4 | |
| SCHEMBL8623337 | 0.82 | FFAR1 (0.59) | FFAR1PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117982-A1 | HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR INHIBITING LIPID ACCUMULATION CONTAINING SAME | CRYSTAL GENOMICS, INC. (KR) | 2008-10-02 | — | — | WO | disclosed |