Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | PPARG | P37231 | 8/20 | 0.48 |
| ▸ | PPARA | Q07869 | 8/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | DRD4 | P21917 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.41 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5111304 | 0.86 | FFAR1 (0.58) | FFAR1PPARGPPARAHRH3DRD2 | |
| SCHEMBL5099205 | 0.85 | FFAR1 (0.60) | FFAR1PPARGPPARAHRH3DRD2 | |
| SCHEMBL4748088 | 0.84 | FFAR1 (0.59) | FFAR1PPARGPPARAHRH3DRD2 | |
| SCHEMBL8839766 | 0.84 | FFAR1 (0.50) | FFAR1RAB9ANPC1PPARGPPARA | |
| SCHEMBL7159209 | 0.84 | FFAR1 (0.56) | FFAR1PPARGPPARAHRH3DRD2 | |
| SCHEMBL4746580 | 0.84 | FFAR1 (0.56) | FFAR1PPARGPPARAHRH3DRD2 | |
| SCHEMBL13542481 | 0.83 | PPARG (0.62) | FFAR1PPARGPPARAKMT2AMEN1 | |
| SCHEMBL4747685 | 0.83 | FFAR1 (0.52) | FFAR1RAB9APPARGPPARAHRH3 | |
| SCHEMBL8623337 | 0.82 | FFAR1 (0.59) | FFAR1PPARGPPARAKMT2AALDH1A1 | |
| SCHEMBL8839914 | 0.82 | FFAR1 (0.54) | FFAR1PPARGPPARAMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6617343-B1 | Treating non-insulin-dependent diabetes mellitus | ELI LILLY AND COMPANY | 2003-09-09 | — | — | US | disclosed |