SCHEMBL4746602

SCHEMBL4746602

NC(=S)SC(SC(N)=S)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 2/20 0.39
F2 P00734 1/20 0.39
ALDH1A1 P00352 2/20 0.37
TP53 P04637 1/20 0.37
TYR P14679 1/20 0.37
TSHR P16473 1/20 0.37
TAS2R38 P59533 1/20 0.37
HSD17B10 Q99714 1/20 0.37
SLC6A2 P23975 1/20 0.36
SLC6A4 P31645 1/20 0.36
SLC6A3 Q01959 1/20 0.36
HTR2A P28223 1/20 0.36
TAAR1 Q96RJ0 1/20 0.36
ADRA2A P08913 1/20 0.35
ADRA2C P18825 1/20 0.35
LMNA P02545 1/20 0.35
HIF1A Q16665 1/20 0.35
KDM4E B2RXH2 1/20 0.35
NOS2 P35228 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11568026 0.80 DPP4 (0.42) DPP4F2ALDH1A1TP53TYR
SCHEMBL6064415 0.80 AOC3 (0.41) DPP4F2ALDH1A1TSHRADRA2A
SCHEMBL11568023 0.80 DPP4 (0.42) DPP4F2ALDH1A1TP53TYR
SCHEMBL27566075 0.80 CYP2D6 (0.41) DPP4F2ALDH1A1TP53TYR
SCHEMBL28351658 0.78 ADRA2A (0.42) ALDH1A1TAAR1ADRA2AADRA2CLMNA
SCHEMBL28351657 0.78 ADRA2A (0.42) ALDH1A1TAAR1ADRA2AADRA2CLMNA
SCHEMBL18787059 0.77 ADRA2A (0.41) ALDH1A1TAAR1ADRA2AADRA2CLMNA
SCHEMBL5616716 0.77 ADRA2A (0.41) ALDH1A1TAAR1ADRA2AADRA2CLMNA
SCHEMBL4801466 0.74 TSHR (0.44) DPP4F2ALDH1A1TP53TYR
SCHEMBL1004825 0.74 CYP2C19 (0.33) DPP4F2ALDH1A1TP53TYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1200540-A4 MINERAL GEAR OILS AND TRANSMISSION FLUIDS LUBRIZOL CORP (US) 2008-09-03 EP disclosed
US-6962895-B2 Lubricating compositions THE LUBRIZOL CORPORATION (US) 2005-11-08 US disclosed
EP-0786511-B1 Lubricating compositions LUBRIZOL CORP (US) 2005-06-15 EP disclosed
US-6872693-B2 Mineral gear oils and transmission fluids THE LUBRIZOL CORPORATION (US) 2005-03-29 US disclosed
US-20030139303-A1 LUBRICATING COMPOSITIONS SCHARF CURTIS R (US) 2003-07-24 US disclosed
US-20030000866-A1 Mineral gear oils and transmission fluids LUBRIZOL CORPORATION, THE 2003-01-02 US disclosed
US-20020119895-A1 LUBRICANTS WITH MOLYBDENUM CONTAINING COMPOSITIONS AND METHODS OF USING THE SAME ELF ANTAR FRANCE (FR) 2002-08-29 US disclosed
EP-0604232-B1 Gear oil lubricating composition containing sulfite or sulfate overbased metal salts LUBRIZOL CORP (US) 2002-05-08 EP disclosed
EP-1200540-A1 MINERAL GEAR OILS AND TRANSMISSION FLUIDS THE LUBRIZOL CORPORATION (US) 2002-05-02 EP disclosed
US-20010056042-A1 Organophosphoryl borates and lubricants and aqueous fluids containing the same SCHWIND JAMES J (US) 2001-12-27 US disclosed
EP-0638631-A1 Lubricating compositions, greases, and aqueous fluids containing the combination of a dithiocarbamate compound and an organic polysulfide THE LUBRIZOL CORPORATION (US) 1995-02-15 EP disclosed
EP-0604232-A1 Lubricants, functional fluid and grease compositions containing sulfite or sulfate overbased metal salts The Lubrizol Corporation (US) 1994-06-29 EP disclosed
EP-0570564-A1 ORGANOPHOSPHORYL BORATES AND LUBRICANTS AND AQUEOUS FLUIDS CONTAINING THE SAME THE LUBRIZOL CORPORATION (US) 1993-11-24 EP disclosed
WO-1993011137-A1 ORGANOPHOSPHORYL BORATES AND LUBRICANTS AND AQUEOUS FLUIDS CONTAINING THE SAME THE LUBRIZOL CORPORATION (US) 1993-06-10 WO disclosed
EP-0537338-A1 THERMALLY STABLE COMPOSITIONS AND LUBRICANTS AND FUNCTIONAL FLUIDS CONTAINING THE SAME. LUBRIZOL CORP (US) 1993-04-21 EP disclosed
US-5147572-A Metal salt of phosphorus acid derivative, dithiocarbamate THE LUBRIZOL CORPORATION (US) 1992-09-15 US disclosed
US-5094746-A Metal salt of a phosphorus acid, a dithiocarbamate and a thionocarbamate THE LUBRIZOL CORPORATION (US) 1992-03-10 US disclosed
WO-1991019569-A1 ORE FLOTATION PROCESS USING CARBAMATE COMPOUNDS THE LUBRIZOL CORPORATION (US) 1991-12-26 WO disclosed
WO-1991019570-A1 A FLOTATION PROCESS USING A MIXTURE OF COLLECTORS THE LUBRIZOL CORPORATION (US) 1991-12-26 WO disclosed
US-5015368-A Ore flotation process using carbamate compounds THE LUBRIZOL CORPORATION (US) 1991-05-14 US disclosed