SCHEMBL1004825

SCHEMBL1004825

C=CC(SC(N)=S)c1ccccc1

nearest known ligand 0.34

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.33
DPP4 P27487 2/20 0.32
F2 P00734 1/20 0.32
ALDH1A1 P00352 2/20 0.31
TP53 P04637 1/20 0.31
TYR P14679 1/20 0.31
TSHR P16473 1/20 0.31
TAS2R38 P59533 1/20 0.31
HSD17B10 Q99714 1/20 0.31
LMNA P02545 2/20 0.31
NOS2 P35228 1/20 0.31
ADRA2A P08913 1/20 0.31
ADRA2C P18825 1/20 0.31
HIF1A Q16665 1/20 0.31
KDM4E B2RXH2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11500737 0.81 CYP2D6 (0.41) CYP2C19DPP4F2NOS2
SCHEMBL2046183 0.81 LMNA (0.37) CYP2C19ALDH1A1HSD17B10LMNAHIF1A
SCHEMBL4746602 0.74 DPP4 (0.39) DPP4F2ALDH1A1TP53TYR
SCHEMBL2152870 0.74 ALDH1A1 (0.43) CYP2C19ALDH1A1TP53TSHRHSD17B10
SCHEMBL776296 0.73 CYP2C19 (0.36) CYP2C19DPP4F2ALDH1A1TSHR
SCHEMBL776368 0.73 CYP2C19 (0.36) CYP2C19DPP4F2ALDH1A1TP53
SCHEMBL11568026 0.72 DPP4 (0.42) DPP4F2ALDH1A1TP53TYR
SCHEMBL11568023 0.72 DPP4 (0.42) DPP4F2ALDH1A1TP53TYR
SCHEMBL6064415 0.72 AOC3 (0.41) DPP4F2ALDH1A1TSHRLMNA
SCHEMBL27566075 0.72 CYP2D6 (0.41) CYP2C19DPP4F2ALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7964692-B2 Polymer obtained by addition-polymerization initiated by a silicon compound JNC CORPORATION (JP) 2011-06-21 US claimed
US-7863396-B2 Silicon compounds CHISSO CORPORATION (JP) 2011-01-04 US claimed
US-11912952-B2 Material and sliding system KYOTO UNIVERSITY (JP) 2024-02-27 US disclosed
EP-3438231-B1 MATERIAL FOR SLIDE MECHANISMS COMPRISING A POLYMER BRUSH UNIV KYOTO (JP) 2023-08-02 EP disclosed
US-20230034470-A1 MATERIAL AND SLIDING SYSTEM National Institute of Technology (JP) 2023-02-02 US disclosed
US-11168170-B2 Clearance narrowing material, clearance narrowing material composite, and article using same KYOTO UNIVERSITY (JP) 2021-11-09 US disclosed
US-20200181309-A1 CLEARANCE NARROWING MATERIAL, CLEARANCE NARROWING MATERIAL COMPOSITE, AND ARTICLE USING SAME KYOTO UNIVERSITY (JP) 2020-06-11 US disclosed
US-20190119596-A1 LUBRICANT AND SRT MATERIAL KYOTO UNIVERSITY (JP) 2019-04-25 US disclosed
EP-3438231-A1 LUBRICANT AND SRT MATERIAL Kyoto University (JP) 2019-02-06 EP disclosed
EP-1548020-B1 SILICON COMPOUND JNC CORP (JP) 2014-07-23 EP disclosed
US-8293442-B2 Resin particle, toner, and image forming method and process cartridge using the same RICOH COMPANY, LTD. (JP) 2012-10-23 US disclosed
US-20060175684-A1 Organosilicon compound JNC PETROCHEMICAL CORPORATION (JP) 2006-08-10 US disclosed
EP-1686133-A2 Organosilicon compound CHISSO CORPORATION (JP) 2006-08-02 EP disclosed
US-20060094849-A1 Silicon compound JNC CORPORATION (JP) 2006-05-04 US disclosed
EP-1650214-A2 Silicon compound CHISSO CORPORATION (JP) 2006-04-26 EP disclosed
US-20050288468-A1 Cyclic polysilsequisiloxanes substituted with a group containing a sulfonyl halide, especially ahalosulfonylphenyl group; living radical polymerization initiators, particularly for preparing acrylic polymers JNC CORPORATION (JP) 2005-12-29 US disclosed
US-20050250925-A1 Silicon compound JNC CORPORATION (JP) 2005-11-10 US disclosed
EP-1550664-A1 SILICON COMPOUND CHISSO CORPORATION (JP) 2005-07-06 EP disclosed
EP-1548020-A1 SILICON COMPOUND CHISSO CORPORATION (JP) 2005-06-29 EP disclosed
US-20050049381-A1 Silicon compounds YAMAHIRO MIKIO (JP) 2005-03-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050288468-A1 Cyclic polysilsequisiloxanes substituted with a group containing a sulfonyl halide, especially ahalosulfonylphenyl group; living radical polymerization initiators, particularly for preparing acrylic polymers STS, SULT1A1, SRM CYP2C19 680/4885DPP4 3276/4885F2 1990/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.