Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 8/20 | 0.49 |
| ▸ | PPARA | Q07869 | 7/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | PPARD | Q03181 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4748552 | 0.93 | PPARG (0.49) | PPARGPPARACYP2C9 | |
| SCHEMBL4743673 | 0.92 | PPARG (0.49) | PPARGPPARACYP2C9KCNH2MAOB | |
| SCHEMBL4748410 | 0.92 | PPARG (0.49) | PPARGPPARACYP2C9KCNH2MAOB | |
| SCHEMBL4748033 | 0.91 | PPARG (0.54) | PPARGPPARAMAOBPOLBFFAR1 | |
| SCHEMBL4747967 | 0.91 | PPARG (0.53) | PPARGPPARACYP2C9KCNH2PTPN1 | |
| SCHEMBL4747043 | 0.91 | PPARG (0.50) | PPARGPPARACYP2C9KCNH2PPARD | |
| SCHEMBL4747044 | 0.91 | PPARG (0.50) | PPARGPPARACYP2C9KCNH2PPARD | |
| SCHEMBL4746249 | 0.90 | FFAR1 (0.55) | PPARGPPARAMAOBPOLBFFAR1 | |
| SCHEMBL4788139 | 0.89 | ALDH1A1 (0.51) | PPARGPPARACYP2C9KCNH2PPARD | |
| SCHEMBL4744558 | 0.89 | ALDH1A1 (0.51) | PPARGPPARACYP2C9KCNH2PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117982-A1 | HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR INHIBITING LIPID ACCUMULATION CONTAINING SAME | CRYSTAL GENOMICS, INC. (KR) | 2008-10-02 | — | — | WO | disclosed |