Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.54 |
| ▸ | PPARA | Q07869 | 6/20 | 0.54 |
| ▸ | TP53 | P04637 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4746249 | 0.93 | FFAR1 (0.55) | PPARGPPARATP53POLBMAPT | |
| SCHEMBL4744694 | 0.93 | PPARG (0.55) | PPARGPPARA | |
| SCHEMBL4744410 | 0.92 | PPARG (0.58) | PPARGPPARATP53POLBMAPT | |
| SCHEMBL4748439 | 0.92 | PPARG (0.58) | PPARGPPARATP53POLBMAPT | |
| SCHEMBL4746623 | 0.91 | PPARG (0.49) | PPARGPPARATP53POLBMAPT | |
| SCHEMBL4747418 | 0.90 | PPARG (0.56) | PPARGPPARATP53MAPTKMT2A | |
| SCHEMBL4746707 | 0.90 | PPARG (0.55) | PPARGPPARATP53POLBMAPT | |
| SCHEMBL4746709 | 0.90 | PPARG (0.55) | PPARGPPARATP53POLBMAPT | |
| SCHEMBL4748103 | 0.88 | PPARG (0.53) | PPARGPPARATP53POLBMAPT | |
| SCHEMBL4748101 | 0.88 | PPARG (0.53) | PPARGPPARATP53POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117982-A1 | HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR INHIBITING LIPID ACCUMULATION CONTAINING SAME | CRYSTAL GENOMICS, INC. (KR) | 2008-10-02 | — | — | WO | disclosed |