Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1B | P47901 | 3/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.42 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.42 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.42 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.42 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.42 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4743111 | 0.88 | HRH3 (0.56) | HRH3HRH1HRH4MEN1KMT2A | |
| SCHEMBL4743288 | 0.88 | HRH3 (0.56) | HRH3HRH1HRH4MEN1KMT2A | |
| SCHEMBL4743293 | 0.86 | MEN1 (0.56) | HRH3HRH1HRH4MEN1KMT2A | |
| SCHEMBL4744714 | 0.84 | AVPR1B (0.46) | AVPR1BHRH3HRH1HRH4KCNA5 | |
| SCHEMBL4743109 | 0.82 | HRH3 (0.46) | HRH3HRH1HRH4MEN1KMT2A | |
| SCHEMBL4745334 | 0.82 | HRH3 (0.47) | AVPR1BHRH3HRH4MEN1KMT2A | |
| SCHEMBL4743105 | 0.81 | AVPR1B (0.44) | AVPR1BHRH3PSEN1PSEN2APH1B | |
| SCHEMBL4744692 | 0.80 | KDM4E (0.51) | AVPR1BHRH3HRH4MEN1KMT2A | |
| SCHEMBL4745396 | 0.80 | HRH3 (0.46) | AVPR1BHRH3MEN1KMT2AKCNA5 | |
| SCHEMBL4746716 | 0.79 | HRH3 (0.58) | HRH3MEN1KMT2AKCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008107320-A1 | PIPERIDINE AND PIPERAZINE DERIVATIVES USED AS ANTI-NEOPLASIC AGENTS OR CELL PROLIFERATION INHIBITORS | CEREP (FR) | 2008-09-12 | — | — | WO | disclosed |