Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1B | P47901 | 5/20 | 0.46 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4743259 | 0.90 | AVPR1B (0.43) | AVPR1BKCNA5HRH3KDM4EPOLB | |
| SCHEMBL4743288 | 0.88 | HRH3 (0.56) | KCNA5HRH3HRH4HRH1 | |
| SCHEMBL4743111 | 0.88 | HRH3 (0.56) | KCNA5HRH3HRH4HRH1 | |
| SCHEMBL4743105 | 0.87 | AVPR1B (0.44) | AVPR1BKCNA5HRH3 | |
| SCHEMBL4743293 | 0.87 | MEN1 (0.56) | KCNA5HRH3HRH4HRH1KDM4E | |
| SCHEMBL4744692 | 0.86 | KDM4E (0.51) | AVPR1BKCNA5HRH3HRH4KDM4E | |
| SCHEMBL4745334 | 0.85 | HRH3 (0.47) | AVPR1BKCNA5HRH3HRH4 | |
| SCHEMBL4746674 | 0.84 | AVPR1B (0.46) | AVPR1BKCNA5HRH3HRH4HRH1 | |
| SCHEMBL4745400 | 0.81 | HTR1A (0.50) | AVPR1BKCNA5HRH3 | |
| SCHEMBL4745366 | 0.81 | HRH4 (0.53) | AVPR1BHRH3HRH4HRH1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008107320-A1 | PIPERIDINE AND PIPERAZINE DERIVATIVES USED AS ANTI-NEOPLASIC AGENTS OR CELL PROLIFERATION INHIBITORS | CEREP (FR) | 2008-09-12 | — | — | WO | claimed |
| WO-2008107320-A1 | PIPERIDINE AND PIPERAZINE DERIVATIVES USED AS ANTI-NEOPLASIC AGENTS OR CELL PROLIFERATION INHIBITORS | CEREP (FR) | 2008-09-12 | — | — | WO | disclosed |