Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.57 |
| ▸ | DRD3 | P35462 | 3/20 | 0.57 |
| ▸ | HRH1 | P35367 | 2/20 | 0.57 |
| ▸ | HTR1A | P08908 | 1/20 | 0.57 |
| ▸ | DRD1 | P21728 | 1/20 | 0.57 |
| ▸ | DRD5 | P21918 | 1/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.57 |
| ▸ | HTR2A | P28223 | 1/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.57 |
| ▸ | HTR7 | P34969 | 1/20 | 0.57 |
| ▸ | HTR2B | P41595 | 1/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.51 |
| ▸ | DRD4 | P21917 | 1/20 | 0.51 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4746228 | 0.90 | DRD2 (0.69) | DRD2DRD3HRH1HTR1ADRD1 | |
| SCHEMBL4747531 | 0.85 | DRD2 (0.58) | DRD2DRD3HRH1HRH3HRH4 | |
| SCHEMBL4743808 | 0.85 | HRH4 (0.64) | DRD2DRD3HRH1HTR1ADRD1 | |
| SCHEMBL4746238 | 0.81 | HRH3 (0.65) | HRH1HRH3HRH4MEN1KMT2A | |
| SCHEMBL4743140 | 0.78 | HRH3 (0.65) | DRD2HRH1HRH3HRH4MEN1 | |
| SCHEMBL7367224 | 0.77 | HRH3 (0.81) | HRH3HRH4MEN1KMT2AALDH1A1 | |
| SCHEMBL4743300 | 0.77 | HRH3 (0.57) | DRD2HRH1HRH3HRH4MEN1 | |
| SCHEMBL4745332 | 0.77 | HRH3 (0.57) | DRD2HRH1HRH3HRH4MEN1 | |
| Hydrochloric Acid SCHEMBL7371901 | 0.76 | HRH3 (0.79) | HRH3HRH4MEN1KMT2AALDH1A1 | |
| SCHEMBL4747562 | 0.75 | HRH3 (0.55) | DRD2HRH1HRH3HRH4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008107320-A1 | PIPERIDINE AND PIPERAZINE DERIVATIVES USED AS ANTI-NEOPLASIC AGENTS OR CELL PROLIFERATION INHIBITORS | CEREP (FR) | 2008-09-12 | — | — | WO | claimed |