Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4746684 | 0.87 | HRH4 (0.55) | KDM4EALDH1A1RAB9AHRH3HRH4 | |
| SCHEMBL4814712 | 0.86 | KDM4E (0.50) | KDM4EALDH1A1RAB9AHRH3 | |
| SCHEMBL4745391 | 0.84 | HRH3 (0.67) | KDM4EALDH1A1KMT2AHRH3HRH4 | |
| SCHEMBL4746206 | 0.83 | HRH3 (0.57) | MEN1KMT2AHRH3 | |
| SCHEMBL4743300 | 0.83 | HRH3 (0.57) | MEN1KMT2AHRH3HRH4 | |
| SCHEMBL4745363 | 0.82 | HRH3 (0.56) | MEN1KMT2AHRH3 | |
| SCHEMBL4744711 | 0.82 | HRH3 (0.56) | MEN1KMT2AHRH3 | |
| SCHEMBL4746222 | 0.80 | HRH3 (0.54) | MEN1KMT2AHRH3 | |
| SCHEMBL4747468 | 0.80 | HRH3 (0.54) | MEN1KMT2AHRH3 | |
| SCHEMBL13150585 | 0.80 | DRD3 (0.65) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008107320-A1 | PIPERIDINE AND PIPERAZINE DERIVATIVES USED AS ANTI-NEOPLASIC AGENTS OR CELL PROLIFERATION INHIBITORS | CEREP (FR) | 2008-09-12 | — | — | WO | disclosed |