(Chloromethyl)Benzene

(Chloromethyl)Benzene

SCHEMBL4746769

ClCc1ccccc1.ClCc1ccccc1

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CALM1 P0DP23 1/20 0.53
TSHR P16473 3/20 0.47
ALDH1A1 P00352 2/20 0.47
LOXL2 Q9Y4K0 2/20 0.47
IDO1 P14902 2/20 0.47
TP53 P04637 1/20 0.47
TRPA1 O75762 1/20 0.47
SIGMAR1 Q99720 1/20 0.46
MAOB P27338 1/20 0.45
HPGD P15428 1/20 0.45
ALOX15 P16050 1/20 0.45
ALOX12 P18054 1/20 0.45
CASP1 P29466 1/20 0.45
HSD17B10 Q99714 1/20 0.45
F2 P00734 1/20 0.43
PLG P00747 1/20 0.43
ELANE P08246 1/20 0.43
CTSG P08311 1/20 0.43
CMA1 P23946 1/20 0.43
CTRC Q99895 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
(Chloromethyl)Benzene SCHEMBL1331085 1.00
(Chloromethyl)Benzene SCHEMBL29919724 1.00
SCHEMBL21317609 1.00 CALM1 (0.53) CALM1TSHRALDH1A1LOXL2IDO1
(Chloromethyl)Benzene SCHEMBL29794364 1.00
(Chloromethyl)Benzene SCHEMBL7413 1.00
(Chloromethyl)Benzene SCHEMBL1616642 1.00
(Chloromethyl)Benzene SCHEMBL6422666 1.00 CALM1 (0.53) CALM1TSHRALDH1A1LOXL2IDO1
(Chloromethyl)Benzene SCHEMBL7634625 0.97 CALM1 (0.50) CALM1TSHRALDH1A1LOXL2IDO1
(Chloromethyl)Benzene SCHEMBL712801 0.97 CALM1 (0.50) CALM1TSHRALDH1A1LOXL2IDO1
(Chloromethyl)Benzene SCHEMBL7537274 0.97

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11685702-B2 Method for producing arene compounds and arene compounds produced by the same JSI SILICONE CO. (KR) 2023-06-27 US disclosed
US-20210188739-A1 METHOD FOR PRODUCING ARENE COMPOUNDS AND ARENE COMPOUNDS PRODUCED BY THE SAME JSI SILICONE CO. (KR) 2021-06-24 US disclosed
WO-2020035432-A1 AN AQUEOUS, STORAGE-STABLE COMPOSITION CONTAINING N-BENZYL-SUBSTITUTED N-(2-AMINOETHYL)-3-AMINOPROPYLSILOXANE HYDROCHLORIDES, PROCESSES FOR PRODUCTION THEREOF AND USE THEREOF EVONIK DEGUSSA GMBH (DE) 2020-02-20 WO disclosed
CN-103214450-B 1-(benzo [D] [1,3] dioxole-5-base)-N-(phenyl) cyclopropane-carboxamides derivatives as ATP-binding cassette transport protein regulator 弗特克斯药品有限公司 2016-10-05 CN disclosed
CN-105749850-A Special reactor for oriented synthesis of p-chlorotoluene 南京科技职业学院 2016-07-13 CN disclosed
CN-103214450-A Modulators of atp-binding cassette transporters VERTEX PHARMA 2013-07-24 CN disclosed
CN-101395147-B 1- (benzo [ D ] [1,3] dioxol-5-yl) -N- (phenyl) cyclopropane-carboxamide derivatives and related compounds as modulators of ATP-binding cassette transporters for the treatment of cystic fibrosis VERTEX PHARMA 2013-05-29 CN disclosed
CN-102702078-A Method for preparing donepezil hydrochloride YANGZIJIANG PHARMACEUTICAL GROUP JIANGSU HAICI BIOLOG PHARMACEUTICAL CO LTD 2012-10-03 CN disclosed
CN-101395147-A 1- (benzo [ D ] [1,3] dioxol-5-yl) -N- (phenyl) cyclopropane-carboxamide derivatives and related compounds as modulators of ATP-binding cassette transporters for the treatment of cystic fibrosis VERTEX PHARMA (US) 2009-03-25 CN disclosed
WO-2008121322-A1 A METHOD OF TREATING NEUROBLASTOMA DUKE UNIVERSITY (US) 2008-10-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210188739-A1 METHOD FOR PRODUCING ARENE COMPOUNDS AND ARENE COMPOUNDS PRODUCED BY THE SAME PFAS, FRK, AGPAT2 CALM1 2648/4885TSHR 2847/4885ALDH1A1 676/4885
US-11685702-B2 Method for producing arene compounds and arene compounds produced by the same PFAS, FRK, AGPAT2 CALM1 2648/4885TSHR 2847/4885ALDH1A1 676/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.