Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.54 |
| ▸ | MEN1 | O00255 | 8/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.54 |
| ▸ | HTT | P42858 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 8/20 | 0.52 |
| ▸ | LMNA | P02545 | 7/20 | 0.52 |
| ▸ | NPC1 | O15118 | 6/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.52 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4746872 | 0.83 | MAPT (0.55) | MAPTMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL14042492 | 0.74 | DYRK1A (0.42) | MAPTMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL4788500 | 0.73 | MAPT (0.69) | MAPTMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL4788498 | 0.73 | MAPT (0.69) | MAPTMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL4788491 | 0.73 | MAPT (0.69) | MAPTMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL10814398 | 0.72 | MEN1 (0.83) | MAPTMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL10922779 | 0.72 | GSTO1 (0.74) | MAPTMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL4788555 | 0.71 | MAPT (0.55) | MAPTMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL4788550 | 0.71 | MAPT (0.55) | MAPTMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL4788085 | 0.71 | MAPT (0.61) | MAPTMEN1KMT2ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008124000-A2 | THIAZOLE DERIVATIVES AS ANDROGEN RECEPTOR MODULATOR COMPOUNDS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2008-10-16 | — | — | WO | claimed |
| WO-2008124000-A2 | THIAZOLE DERIVATIVES AS ANDROGEN RECEPTOR MODULATOR COMPOUNDS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2008-10-16 | — | — | WO | disclosed |