Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.61 |
| ▸ | LMNA | P02545 | 7/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.61 |
| ▸ | MEN1 | O00255 | 8/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.61 |
| ▸ | HTT | P42858 | 3/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | GSTO1 | P78417 | 2/20 | 0.55 |
| ▸ | PARP1 | P09874 | 1/20 | 0.54 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 7/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 5/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.52 |
| ▸ | RELA | Q04206 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4788500 | 0.94 | MAPT (0.69) | MAPTSMN1; SMN2LMNAKDM4EMEN1 | |
| SCHEMBL4788498 | 0.94 | MAPT (0.69) | MAPTSMN1; SMN2LMNAKDM4EMEN1 | |
| SCHEMBL4788491 | 0.94 | MAPT (0.69) | MAPTSMN1; SMN2LMNAKDM4EMEN1 | |
| SCHEMBL4787032 | 0.90 | SMN1; SMN2 (0.66) | MAPTSMN1; SMN2LMNAKDM4EMEN1 | |
| SCHEMBL4786629 | 0.88 | MAPT (0.78) | MAPTSMN1; SMN2LMNAKDM4EMEN1 | |
| SCHEMBL4785626 | 0.88 | SMN1; SMN2 (0.78) | MAPTSMN1; SMN2LMNAKDM4EMEN1 | |
| SCHEMBL4786640 | 0.88 | MAPT (0.78) | MAPTSMN1; SMN2LMNAKDM4EMEN1 | |
| SCHEMBL4788877 | 0.88 | MAPT (0.59) | MAPTSMN1; SMN2LMNAKDM4EMEN1 | |
| SCHEMBL4785620 | 0.88 | KMT2A (0.59) | MAPTSMN1; SMN2LMNAKDM4EMEN1 | |
| SCHEMBL4786426 | 0.88 | SMN1; SMN2 (0.59) | MAPTSMN1; SMN2LMNAKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008124000-A2 | THIAZOLE DERIVATIVES AS ANDROGEN RECEPTOR MODULATOR COMPOUNDS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2008-10-16 | — | — | WO | claimed |
| WO-2008124000-A2 | THIAZOLE DERIVATIVES AS ANDROGEN RECEPTOR MODULATOR COMPOUNDS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2008-10-16 | — | — | WO | disclosed |
| WO-2008124000-A2 | THIAZOLE DERIVATIVES AS ANDROGEN RECEPTOR MODULATOR COMPOUNDS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2008-10-16 | — | — | WO | disclosed |