Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 8/20 | 0.53 |
| ▸ | CCR4 | P51679 | 1/20 | 0.50 |
| ▸ | EHMT2 | Q96KQ7 | 3/20 | 0.47 |
| ▸ | EHMT1 | Q9H9B1 | 2/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.47 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.47 |
| ▸ | NSD2 | O96028 | 2/20 | 0.42 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4747115 | 0.79 | PDPK1 (0.55) | PDPK1 | |
| SCHEMBL4747760 | 0.78 | PDPK1 (0.56) | PDPK1PDGFRBPDGFRA | |
| SCHEMBL4746478 | 0.77 | PDPK1 (0.52) | PDPK1 | |
| SCHEMBL4747109 | 0.77 | PDPK1 (0.70) | PDPK1 | |
| SCHEMBL4747754 | 0.76 | PDPK1 (0.68) | PDPK1 | |
| SCHEMBL4744364 | 0.75 | PDPK1 (0.54) | PDPK1 | |
| SCHEMBL4745705 | 0.75 | PDPK1 (0.54) | PDPK1 | |
| SCHEMBL4929414 | 0.74 | PDPK1 (0.58) | PDPK1 | |
| SCHEMBL4745738 | 0.74 | PDPK1 (0.61) | PDPK1 | |
| SCHEMBL4744086 | 0.73 | PDPK1 (0.68) | PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008109599-A1 | PYRIMIDO [5,4-C] QUINOLINE-2, 4-DIAMINE DERIVATIVES AND METHODS OF USE THEREOF | WYETH (US) | 2008-09-12 | — | — | WO | disclosed |