Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.36 |
| ▸ | RBP1 | P09455 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4747652 | 0.91 | KMT2A (0.52) | ALDH1A1KMT2AMEN1DRD2DRD3 | |
| SCHEMBL4748236 | 0.91 | DRD2 (0.46) | ALDH1A1KMT2AMEN1DRD2DRD3 | |
| SCHEMBL4744996 | 0.91 | DRD2 (0.46) | ALDH1A1KMT2AMEN1DRD2DRD4 | |
| SCHEMBL4744655 | 0.89 | DRD2 (0.46) | ALDH1A1KMT2AMEN1DRD2DRD4 | |
| SCHEMBL4745089 | 0.88 | DRD2 (0.45) | ALDH1A1KMT2AMEN1DRD2DRD4 | |
| SCHEMBL4746736 | 0.87 | MEN1 (0.49) | ALDH1A1KMT2AMEN1HSD11B1DRD2 | |
| SCHEMBL4747795 | 0.87 | DRD2 (0.47) | ALDH1A1KMT2AMEN1DRD2DRD4 | |
| SCHEMBL4813265 | 0.87 | DRD2 (0.43) | ALDH1A1KMT2AMEN1DRD2DRD3 | |
| SCHEMBL4744225 | 0.86 | KMT2A (0.43) | ALDH1A1KMT2AMEN1HSD11B1DRD2 | |
| SCHEMBL4748294 | 0.85 | KMT2A (0.49) | ALDH1A1KMT2AMEN1HSD11B1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117148-A1 | SUBSTITUTED OXADIAZOLE ANALOGS AS CALCIUM CHANNEL ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2008-10-02 | — | — | WO | claimed |
| WO-2008117148-A1 | SUBSTITUTED OXADIAZOLE ANALOGS AS CALCIUM CHANNEL ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2008-10-02 | — | — | WO | disclosed |