Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | DRD4 | P21917 | 2/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.38 |
| ▸ | NPY1R | P25929 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.35 |
| ▸ | TUBB | P07437 | 1/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4746791 | 0.91 | KMT2A (0.51) | DRD2ALDH1A1MEN1KMT2ADRD4 | |
| SCHEMBL4747161 | 0.91 | ALDH1A1 (0.46) | DRD2ALDH1A1MEN1KMT2ADRD4 | |
| SCHEMBL4747652 | 0.87 | KMT2A (0.52) | DRD2ALDH1A1MEN1KMT2ADRD4 | |
| SCHEMBL4744996 | 0.86 | DRD2 (0.46) | DRD2ALDH1A1MEN1KMT2ADRD4 | |
| SCHEMBL4748754 | 0.86 | MEN1 (0.45) | DRD2ALDH1A1MEN1KMT2ADRD4 | |
| SCHEMBL4744655 | 0.85 | DRD2 (0.46) | DRD2ALDH1A1MEN1KMT2ADRD4 | |
| SCHEMBL4744808 | 0.85 | DRD2 (0.45) | DRD2ALDH1A1MEN1KMT2ADRD4 | |
| SCHEMBL4746781 | 0.84 | MEN1 (0.46) | DRD2ALDH1A1MEN1KMT2ADRD4 | |
| SCHEMBL4745089 | 0.84 | DRD2 (0.45) | DRD2ALDH1A1MEN1KMT2ADRD4 | |
| Hydrochloric Acid SCHEMBL4744993 | 0.84 | DRD2 (0.44) | DRD2ALDH1A1MEN1KMT2ADRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117148-A1 | SUBSTITUTED OXADIAZOLE ANALOGS AS CALCIUM CHANNEL ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2008-10-02 | — | — | WO | claimed |
| WO-2008117148-A1 | SUBSTITUTED OXADIAZOLE ANALOGS AS CALCIUM CHANNEL ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2008-10-02 | — | — | WO | disclosed |