Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.68 |
| ▸ | ACACB | O00763 | 3/20 | 0.48 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.46 |
| ▸ | HAO1 | Q9UJM8 | 2/20 | 0.44 |
| ▸ | FBP1 | P09467 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MGAM | O43451 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | SI | P14410 | 2/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | BCR | P11274 | 1/20 | 0.33 |
| ▸ | ADK | P55263 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30278513 | 0.81 | GRM5 (0.68) | GRM5ACACBPDE10AHAO1FBP1 | |
| SCHEMBL6313587 | 0.81 | GRM5 (0.68) | GRM5ACACBPDE10AHAO1FBP1 | |
| SCHEMBL6311975 | 0.81 | GRM5 (1.00) | GRM5ACACBPDE10AHAO1 | |
| SCHEMBL15870993 | 0.79 | GRM5 (0.68) | GRM5ACACBPDE10AHAO1FBP1 | |
| SCHEMBL10236313 | 0.77 | GRM5 (0.62) | GRM5ACACBPDE10AHAO1 | |
| SCHEMBL702812 | 0.77 | GRM5 (0.62) | GRM5ACACBPDE10AHAO1FBP1 | |
| SCHEMBL20015760 | 0.72 | CYP2A6 (0.57) | ACACBMEN1KMT2AADKALDH1A1 | |
| SCHEMBL1246271 | 0.72 | CYP2A6 (0.57) | ACACBMEN1KMT2AADKALDH1A1 | |
| SCHEMBL4854409 | 0.71 | GRM5 (0.69) | GRM5 | |
| SCHEMBL13218217 | 0.69 | GRM5 (0.51) | GRM5ACACBPDE10AHAO1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008125599-A1 | 2-CARBOXY THIOPHENE DERIVATIVES AS ANTI-VIRAL AGENTS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-10-23 | — | — | WO | disclosed |