Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 12/20 | 0.47 |
| ▸ | PPARA | Q07869 | 11/20 | 0.47 |
| ▸ | PPARD | Q03181 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4744868 | 0.94 | PPARA (0.51) | PPARGPPARAPPARD | |
| SCHEMBL4744013 | 0.89 | PPARA (0.54) | PPARGPPARAPPARD | |
| SCHEMBL4744642 | 0.88 | PPARG (0.55) | PPARGPPARACYP2C9KCNH2PTPN1 | |
| SCHEMBL4744698 | 0.84 | FFAR1 (0.63) | PPARGPPARAFFAR1MAPT | |
| SCHEMBL4745030 | 0.83 | PPARG (0.59) | PPARGPPARAPPARDFFAR1 | |
| SCHEMBL4746620 | 0.80 | PPARA (0.55) | PPARGPPARACYP2C9KCNH2 | |
| SCHEMBL4743931 | 0.80 | KDR (0.61) | PPARGPPARACYP2C9KCNH2FFAR1 | |
| SCHEMBL4748548 | 0.78 | PPARG (0.55) | PPARGPPARACYP2C9KCNH2MAPT | |
| SCHEMBL21618308 | 0.78 | HTR2C (0.46) | — | |
| SCHEMBL4743666 | 0.77 | KDR (0.60) | PPARGPPARACYP2C9KCNH2FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117982-A1 | HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR INHIBITING LIPID ACCUMULATION CONTAINING SAME | CRYSTAL GENOMICS, INC. (KR) | 2008-10-02 | — | — | WO | disclosed |