Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 17/20 | 0.56 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.54 |
| ▸ | PPARA | Q07869 | 16/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4747380 | 1.00 | PPARG (0.56) | PPARGCD274PPARAPOLBSPHK1 | |
| SCHEMBL4744750 | 0.91 | PPARG (0.55) | PPARGCD274PPARA | |
| SCHEMBL4744752 | 0.91 | PPARG (0.55) | PPARGCD274PPARA | |
| SCHEMBL4746302 | 0.88 | PPARG (0.58) | PPARGPPARA | |
| SCHEMBL4746305 | 0.88 | PPARG (0.58) | PPARGPPARA | |
| SCHEMBL4747524 | 0.87 | PPARG (0.60) | PPARGCD274PPARA | |
| SCHEMBL4744012 | 0.85 | CD274 (0.61) | PPARGCD274PPARAPOLBSPHK1 | |
| SCHEMBL4744628 | 0.85 | CD274 (0.61) | PPARGCD274PPARAPOLBSPHK1 | |
| SCHEMBL4747333 | 0.84 | LTA4H (0.53) | PPARGPPARA | |
| SCHEMBL4743664 | 0.84 | CD274 (0.60) | PPARGCD274PPARAPOLBSPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117982-A1 | HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR INHIBITING LIPID ACCUMULATION CONTAINING SAME | CRYSTAL GENOMICS, INC. (KR) | 2008-10-02 | — | — | WO | claimed |
| WO-2008117982-A1 | HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR INHIBITING LIPID ACCUMULATION CONTAINING SAME | CRYSTAL GENOMICS, INC. (KR) | 2008-10-02 | — | — | WO | disclosed |