Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 18/20 | 0.55 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.51 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 9/20 | 0.48 |
| ▸ | PPARD | Q03181 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4744750 | 1.00 | PPARG (0.55) | PPARGCD274PDCD1PPARAPPARD | |
| SCHEMBL4747333 | 0.93 | LTA4H (0.53) | PPARGPPARAPPARD | |
| SCHEMBL4747382 | 0.91 | PPARG (0.56) | PPARGCD274PPARA | |
| SCHEMBL4747380 | 0.91 | PPARG (0.56) | PPARGCD274PPARA | |
| SCHEMBL4748485 | 0.89 | PPARG (0.62) | PPARGPPARAPPARD | |
| SCHEMBL4748488 | 0.89 | PPARG (0.62) | PPARGPPARAPPARD | |
| SCHEMBL4748313 | 0.87 | PPARG (0.60) | PPARGPPARAPPARD | |
| SCHEMBL4748310 | 0.87 | PPARG (0.60) | PPARGPPARAPPARD | |
| SCHEMBL4745027 | 0.86 | PPARG (0.63) | PPARGCD274PPARAPPARD | |
| SCHEMBL4748482 | 0.86 | PPARG (0.63) | PPARGCD274PPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117982-A1 | HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR INHIBITING LIPID ACCUMULATION CONTAINING SAME | CRYSTAL GENOMICS, INC. (KR) | 2008-10-02 | — | — | WO | claimed |
| WO-2008117982-A1 | HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR INHIBITING LIPID ACCUMULATION CONTAINING SAME | CRYSTAL GENOMICS, INC. (KR) | 2008-10-02 | — | — | WO | disclosed |