Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | ATR | Q13535 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8349405 | 0.82 | IGF1R (0.38) | IGF1R | |
| SCHEMBL4631958 | 0.74 | IGF1R (0.34) | IGF1R | |
| SCHEMBL3023200 | 0.74 | ALDH1A1 (0.38) | — | |
| SCHEMBL3641467 | 0.72 | POLB (0.40) | — | |
| SCHEMBL11157283 | 0.70 | ATR (0.38) | CNR1CNR2ATR | |
| SCHEMBL6321766 | 0.67 | CYP1A2 (0.58) | IGF1R | |
| SCHEMBL17016555 | 0.67 | CYP2C9 (0.38) | CNR1CNR2ATR | |
| SCHEMBL28569434 | 0.66 | HSP90AA1 (0.39) | CNR1CNR2ATR | |
| SCHEMBL5407627 | 0.66 | NSD2 (0.42) | IGF1R | |
| SCHEMBL18048110 | 0.66 | ALDH1A1 (0.37) | IGF1RCNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080293711-A1 | Chemokine receptor modulators | METASTATIX, INC. | 2008-11-27 | — | — | US | disclosed |
| WO-2008112156-A1 | CHEMOKINE RECEPTOR MODULATORS | ALTIRIS THERAPEUTICS (US) | 2008-09-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293711-A1 | Chemokine receptor modulators | CCR5, CCL2, CXCR4 | IGF1R 1215/4885CNR1 173/4885CNR2 496/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.