Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 8/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 8/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 6/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 6/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11870839 | 0.83 | CHRNB2 (0.59) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL687248 | 0.83 | TSHR (0.48) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| Trimethylammonium SCHEMBL27718056 | 0.81 | TSHR (0.57) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL1635286 | 0.80 | TSHR (0.46) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL1477898 | 0.80 | TSHR (0.50) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL28454119 | 0.80 | TSHR (0.61) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| Trimethylammonium SCHEMBL28282564 | 0.78 | TSHR (0.48) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL34661 | 0.78 | TSHR (0.63) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL10714314 | 0.78 | TSHR (0.56) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL29550542 | 0.78 | TSHR (0.63) | TSHRALDH1A1TP53HIF1ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008115457-A2 | FLUOROBETAINE COPOLYMER AND FIRE FIGHTING FOAM CONCENTRATES THEREFROM | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-09-25 | — | — | WO | disclosed |
| US-6670508-B2 | Quaternizing 1,3-bis-dimethylamineisopropyl acrylate with benzyl chloride at a temperature of 35-60 degrees C., adding water | ATOFINA (FR) | 2003-12-30 | — | — | US | disclosed |
| US-20030171489-A1 | Saline aqueous dispersions of water soluble (co) polymers based on cationic monomers, method for making same and uses thereof | ATOFINA (FR) | 2003-09-11 | — | — | US | disclosed |
| US-20030166771-A1 | Water soluble saline aqueous dispersion of copolymers based on cationic monomers, method for making same and uses thereof | ATOFINA (FR) | 2003-09-04 | — | — | US | disclosed |
| US-20030153675-A1 | Salt-free aqueous dispersions of water soluble (co) polymers based on cationic monomrs, method for making same and uses thereof | ATOFINA (FR) | 2003-08-14 | — | — | US | disclosed |
| US-20020193545-A1 | Process for manufacturing the chloride of 1,3-bis- (dimethylbenzylammonium) isopropyl, acrylate alone or mixed with other monomers, and corresponding (co) polymers | ATOFINA (FR) | 2002-12-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020193545-A1 | Process for manufacturing the chloride of 1,3-bis- (dimethylbenzylammonium) isopropyl, acrylate alone or mixed with other monomers, and corresponding (co) polymers | CLIC1, C9, INTS9 | TSHR 4332/4885ALDH1A1 1518/4885TP53 3225/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.