Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | CACNA1G | O43497 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SMO | Q99835 | 3/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4744984 | 0.90 | HTR7 (0.46) | HTR7DRD4GRM2CACNA1GLMNA | |
| SCHEMBL4744148 | 0.86 | HTR7 (0.44) | HTR7DRD4GRM2CACNA1GLMNA | |
| SCHEMBL4748749 | 0.86 | HTR7 (0.43) | HTR7DRD4GRM2CACNA1GLMNA | |
| SCHEMBL4748724 | 0.85 | HTR7 (0.45) | HTR7DRD4GRM2LMNAHTT | |
| SCHEMBL4823970 | 0.85 | HTR7 (0.45) | HTR7DRD4GRM2LMNASMN1; SMN2 | |
| SCHEMBL4746801 | 0.85 | HTR7 (0.46) | HTR7DRD4GRM2LMNASMN1; SMN2 | |
| SCHEMBL4744228 | 0.84 | HTR7 (0.43) | HTR7DRD4GRM2CACNA1GLMNA | |
| SCHEMBL4748288 | 0.84 | HTR7 (0.43) | HTR7DRD4GRM2LMNASMN1; SMN2 | |
| SCHEMBL4748632 | 0.84 | HTR7 (0.43) | HTR7DRD4GRM2CACNA1GLMNA | |
| SCHEMBL4744953 | 0.83 | HTR7 (0.43) | HTR7DRD4GRM2CACNA1GLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117148-A1 | SUBSTITUTED OXADIAZOLE ANALOGS AS CALCIUM CHANNEL ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2008-10-02 | — | — | WO | claimed |
| WO-2008117148-A1 | SUBSTITUTED OXADIAZOLE ANALOGS AS CALCIUM CHANNEL ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2008-10-02 | — | — | WO | disclosed |