Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | SMO | Q99835 | 1/20 | 0.39 |
| ▸ | CACNA1G | O43497 | 5/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GALR3 | O60755 | 1/20 | 0.36 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4744228 | 0.92 | HTR7 (0.43) | HTR7CACNA1GDRD4GRM2ALOX5AP | |
| SCHEMBL4744984 | 0.92 | HTR7 (0.46) | HTR7SMOCACNA1GDRD4GRM2 | |
| SCHEMBL4746768 | 0.90 | HTR7 (0.41) | HTR7CACNA1GDRD4GRM2ALOX5AP | |
| SCHEMBL4748337 | 0.90 | HTR7 (0.41) | HTR7SMOCACNA1GDRD4GRM2 | |
| SCHEMBL4747631 | 0.88 | SMN1; SMN2 (0.43) | HTR7CACNA1GDRD4GRM2ALOX5AP | |
| SCHEMBL4744148 | 0.88 | HTR7 (0.44) | HTR7SMOCACNA1GDRD4GRM2 | |
| SCHEMBL4823970 | 0.87 | HTR7 (0.45) | HTR7DRD4GRM2ALOX5APLMNA | |
| SCHEMBL4748724 | 0.87 | HTR7 (0.45) | HTR7SMODRD4GRM2ALOX5AP | |
| SCHEMBL4746801 | 0.86 | HTR7 (0.46) | HTR7DRD4GRM2ALOX5APLMNA | |
| SCHEMBL4747823 | 0.86 | HTR7 (0.44) | HTR7SMOCACNA1GPKMDRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117148-A1 | SUBSTITUTED OXADIAZOLE ANALOGS AS CALCIUM CHANNEL ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2008-10-02 | — | — | WO | claimed |
| WO-2008117148-A1 | SUBSTITUTED OXADIAZOLE ANALOGS AS CALCIUM CHANNEL ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2008-10-02 | — | — | WO | disclosed |