Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | NTSR1 | P30989 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4744413 | 0.98 | MEN1 (0.46) | MEN1KMT2AALDH1A1DRD2GRM2 | |
| SCHEMBL4748282 | 0.94 | DRD2 (0.45) | MEN1KMT2AALDH1A1DRD2GRM2 | |
| SCHEMBL4748742 | 0.94 | KMT2A (0.52) | MEN1KMT2AALDH1A1DRD2GRM2 | |
| SCHEMBL4744808 | 0.93 | DRD2 (0.45) | MEN1KMT2AALDH1A1DRD2GRM2 | |
| SCHEMBL4747647 | 0.93 | MEN1 (0.46) | MEN1KMT2AALDH1A1DRD2GRM2 | |
| SCHEMBL20328212 | 0.92 | DRD2 (0.44) | MEN1KMT2AALDH1A1DRD2GRM2 | |
| Hydrochloric Acid SCHEMBL4744993 | 0.92 | DRD2 (0.44) | MEN1KMT2AALDH1A1DRD2GRM2 | |
| SCHEMBL4744482 | 0.91 | MEN1 (0.46) | MEN1KMT2AALDH1A1DRD2GRM2 | |
| SCHEMBL4747163 | 0.91 | MEN1 (0.45) | MEN1KMT2AALDH1A1DRD2GRM2 | |
| SCHEMBL4748790 | 0.90 | DRD2 (0.46) | MEN1KMT2AALDH1A1DRD2GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117148-A1 | SUBSTITUTED OXADIAZOLE ANALOGS AS CALCIUM CHANNEL ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2008-10-02 | — | — | WO | claimed |
| WO-2008117148-A1 | SUBSTITUTED OXADIAZOLE ANALOGS AS CALCIUM CHANNEL ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2008-10-02 | — | — | WO | disclosed |