Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | NTSR1 | P30989 | 5/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4747647 | 0.98 | MEN1 (0.46) | DRD2MEN1KMT2AALDH1A1GRM2 | |
| SCHEMBL4748742 | 0.94 | KMT2A (0.52) | DRD2MEN1KMT2AALDH1A1GRM2 | |
| SCHEMBL4747840 | 0.94 | MEN1 (0.44) | DRD2MEN1KMT2AALDH1A1GRM2 | |
| SCHEMBL4744808 | 0.94 | DRD2 (0.45) | DRD2MEN1KMT2AALDH1A1GRM2 | |
| SCHEMBL20328212 | 0.93 | DRD2 (0.44) | DRD2MEN1KMT2AALDH1A1GRM2 | |
| Hydrochloric Acid SCHEMBL4744993 | 0.93 | DRD2 (0.44) | DRD2MEN1KMT2AALDH1A1GRM2 | |
| SCHEMBL4744413 | 0.93 | MEN1 (0.46) | DRD2MEN1KMT2AALDH1A1GRM2 | |
| SCHEMBL4747649 | 0.92 | MEN1 (0.44) | DRD2MEN1KMT2AALDH1A1GRM2 | |
| SCHEMBL4744482 | 0.92 | MEN1 (0.46) | DRD2MEN1KMT2AALDH1A1GRM2 | |
| SCHEMBL4747163 | 0.91 | MEN1 (0.45) | DRD2MEN1KMT2AALDH1A1GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117148-A1 | SUBSTITUTED OXADIAZOLE ANALOGS AS CALCIUM CHANNEL ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2008-10-02 | — | — | WO | claimed |
| WO-2018118101-A1 | T-TYPE CALCIUM CHANNEL MODULATORS AND METHODS OF USE THEREOF | PRAXIS PRECISION MEDICINES, INC. (US) | 2018-06-28 | — | — | WO | disclosed |
| WO-2008117148-A1 | SUBSTITUTED OXADIAZOLE ANALOGS AS CALCIUM CHANNEL ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2008-10-02 | — | — | WO | disclosed |