Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 6/20 | 0.48 |
| ▸ | TMEM97 | Q5BJF2 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 4/20 | 0.41 |
| ▸ | HTR7 | P34969 | 4/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | MC4R | P32245 | 1/20 | 0.38 |
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | HRH1 | P35367 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4747565 | 0.94 | GSR (0.48) | GSRTMEM97KDM4EALDH1A1HPGD | |
| SCHEMBL4744199 | 0.89 | KCNH2 (0.48) | GSRTMEM97KDM4EALDH1A1HPGD | |
| SCHEMBL4748220 | 0.89 | GSR (0.48) | GSRTMEM97KDM4EALDH1A1HPGD | |
| SCHEMBL14069128 | 0.86 | MC4R (0.41) | GSRKDM4EALDH1A1HTR7MC4R | |
| SCHEMBL4744550 | 0.86 | TMEM97 (0.47) | GSRTMEM97KDM4EALDH1A1HPGD | |
| SCHEMBL4746291 | 0.85 | TMEM97 (0.49) | GSRTMEM97MC4RNPY1R | |
| SCHEMBL4744200 | 0.83 | GSR (0.46) | GSRKDM4EALDH1A1HPGDHTR1A | |
| SCHEMBL4744848 | 0.81 | GSR (0.40) | GSRHTR7MC4R | |
| SCHEMBL4748222 | 0.75 | HRH3 (0.47) | GSRALDH1A1MC4R | |
| SCHEMBL4744753 | 0.75 | ACP1 (0.40) | GSRMC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008114009-A1 | 10H-BENZO(G)PTERDINE-2,4-DIONE COMPOUNDS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | CAMBRIDGE ENTERPRISE LTD. (GB) | 2008-09-25 | — | — | WO | disclosed |
| WO-2008114009-A1 | 10H-BENZO(G)PTERDINE-2,4-DIONE COMPOUNDS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | CAMBRIDGE ENTERPRISE LTD. (GB) | 2008-09-25 | — | — | WO | disclosed |